Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers
The present study aimed to evaluate the effects of manganese methionine hydroxyl analog chelated (Mn-MHAC) as a manganese (Mn) source on growth performance and trace element deposition in broilers. A total of 432 Arbor Acres commercial female broilers were fed a basal corn-soybean diet containing Mn...
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KeAi Communications Co., Ltd.
2021-06-01
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| Series: | Animal Nutrition |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405654521000378 |
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| author | Tiantian Meng Lumin Gao Chunyan Xie Yangkui Xiang Yiqiang Huang Yawei Zhang Xin Wu |
| author_facet | Tiantian Meng Lumin Gao Chunyan Xie Yangkui Xiang Yiqiang Huang Yawei Zhang Xin Wu |
| author_sort | Tiantian Meng |
| collection | DOAJ |
| description | The present study aimed to evaluate the effects of manganese methionine hydroxyl analog chelated (Mn-MHAC) as a manganese (Mn) source on growth performance and trace element deposition in broilers. A total of 432 Arbor Acres commercial female broilers were fed a basal corn-soybean diet containing Mn at 25.64 mg/kg diet for 10 d. They were then randomly assigned to 6 groups, including a control group (the basal diet), a Mn sulfate group (the basal diet supplemented with Mn at 100 mg/kg diet), and 4 Mn-MHAC groups (the basal diet supplemented with Mn-MHAC at 25, 50, 75 and 100 mg Mn/kg diet, respectively). The results showed that compared with the control group, groups supplemented with Mn-MHAC had a positive effect on BW (quadratic, P = 0.017) and ADG (quadratic, P = 0.017). Moreover, the Mn-MHAC (50 mg Mn/kg diet) group had significantly greater BW and ADG (P < 0.05) compared with the other Mn-MHAC groups. Trace element deposition results also showed that tibial Mn increased (linear or quadratic, P = 0.002 and 0.009, respectively) in groups fed diets with increased levels of Mn-MHAC. In contrast, Fe deposition decreased both in the heart (linear, P = 0.020) and tibia (P < 0.05). In addition, the Mn-MHAC supplement noticeably lowered serum Mn-SOD activity (linear or quadratic, P = 0.048 and 0.019, respectively). The relative mRNA levels of divalent metal transporter 1 (DMT1) (P = 0.024), ferroportin 1 (FPN1) (P = 0.049), and Cu transporter-1(CTR1) (P < 0.001) in the duodenum, as well as CTR1 in the jejunum and ileum (P = 0.040 and 0.011, respectively) were higher in the Mn-supplemented group than in the control group. Furthermore, the relative mRNA level of DMT1 in the jejunum and ileum of broilers in the Mn-MHAC group (50 mg Mn/kg diet) did not differ from those in the control group, but was lower than those in the Mn sulfate group (P < 0.05). In conclusion, Mn-MHAC dietary supplementation improved the growth performance and trace element deposition in broilers. From this study, we recommend the optimum Mn-MHAC level to meet the Mn requirement of broilers is 50 to 75 mg Mn/kg diet. |
| first_indexed | 2024-12-16T23:15:52Z |
| format | Article |
| id | doaj.art-9b4d8e26d9484ed08a01129dbf91a7ea |
| institution | Directory Open Access Journal |
| issn | 2405-6545 |
| language | English |
| last_indexed | 2024-12-16T23:15:52Z |
| publishDate | 2021-06-01 |
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| series | Animal Nutrition |
| spelling | doaj.art-9b4d8e26d9484ed08a01129dbf91a7ea2022-12-21T22:12:18ZengKeAi Communications Co., Ltd.Animal Nutrition2405-65452021-06-0172481487Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilersTiantian Meng0Lumin Gao1Chunyan Xie2Yangkui Xiang3Yiqiang Huang4Yawei Zhang5Xin Wu6CAS Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Changsha, 410125, China; Hunan Co-Innovation Center of Safety Animal Production, College of Animal Science and Technology; College of Resources and Environment, Hunan Agricultural University, Changsha, 410128, ChinaCAS Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Changsha, 410125, ChinaHunan Co-Innovation Center of Safety Animal Production, College of Animal Science and Technology; College of Resources and Environment, Hunan Agricultural University, Changsha, 410128, ChinaHunan Provincial Research Center of Mineral Element Nutrition Engineering Technology, Xing-Jia Bio-engineering Co., Ltd., 410300, Changsha, ChinaHunan Provincial Research Center of Mineral Element Nutrition Engineering Technology, Xing-Jia Bio-engineering Co., Ltd., 410300, Changsha, ChinaHunan Provincial Research Center of Mineral Element Nutrition Engineering Technology, Xing-Jia Bio-engineering Co., Ltd., 410300, Changsha, ChinaCAS Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Changsha, 410125, China; Hunan Co-Innovation Center of Safety Animal Production, College of Animal Science and Technology; College of Resources and Environment, Hunan Agricultural University, Changsha, 410128, China; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China; Corresponding author.The present study aimed to evaluate the effects of manganese methionine hydroxyl analog chelated (Mn-MHAC) as a manganese (Mn) source on growth performance and trace element deposition in broilers. A total of 432 Arbor Acres commercial female broilers were fed a basal corn-soybean diet containing Mn at 25.64 mg/kg diet for 10 d. They were then randomly assigned to 6 groups, including a control group (the basal diet), a Mn sulfate group (the basal diet supplemented with Mn at 100 mg/kg diet), and 4 Mn-MHAC groups (the basal diet supplemented with Mn-MHAC at 25, 50, 75 and 100 mg Mn/kg diet, respectively). The results showed that compared with the control group, groups supplemented with Mn-MHAC had a positive effect on BW (quadratic, P = 0.017) and ADG (quadratic, P = 0.017). Moreover, the Mn-MHAC (50 mg Mn/kg diet) group had significantly greater BW and ADG (P < 0.05) compared with the other Mn-MHAC groups. Trace element deposition results also showed that tibial Mn increased (linear or quadratic, P = 0.002 and 0.009, respectively) in groups fed diets with increased levels of Mn-MHAC. In contrast, Fe deposition decreased both in the heart (linear, P = 0.020) and tibia (P < 0.05). In addition, the Mn-MHAC supplement noticeably lowered serum Mn-SOD activity (linear or quadratic, P = 0.048 and 0.019, respectively). The relative mRNA levels of divalent metal transporter 1 (DMT1) (P = 0.024), ferroportin 1 (FPN1) (P = 0.049), and Cu transporter-1(CTR1) (P < 0.001) in the duodenum, as well as CTR1 in the jejunum and ileum (P = 0.040 and 0.011, respectively) were higher in the Mn-supplemented group than in the control group. Furthermore, the relative mRNA level of DMT1 in the jejunum and ileum of broilers in the Mn-MHAC group (50 mg Mn/kg diet) did not differ from those in the control group, but was lower than those in the Mn sulfate group (P < 0.05). In conclusion, Mn-MHAC dietary supplementation improved the growth performance and trace element deposition in broilers. From this study, we recommend the optimum Mn-MHAC level to meet the Mn requirement of broilers is 50 to 75 mg Mn/kg diet.http://www.sciencedirect.com/science/article/pii/S2405654521000378Manganese methionine hydroxy analog chelatedTrace elementDepositionTransporterBroiler |
| spellingShingle | Tiantian Meng Lumin Gao Chunyan Xie Yangkui Xiang Yiqiang Huang Yawei Zhang Xin Wu Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers Animal Nutrition Manganese methionine hydroxy analog chelated Trace element Deposition Transporter Broiler |
| title | Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers |
| title_full | Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers |
| title_fullStr | Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers |
| title_full_unstemmed | Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers |
| title_short | Manganese methionine hydroxy analog chelated affects growth performance, trace element deposition and expression of related transporters of broilers |
| title_sort | manganese methionine hydroxy analog chelated affects growth performance trace element deposition and expression of related transporters of broilers |
| topic | Manganese methionine hydroxy analog chelated Trace element Deposition Transporter Broiler |
| url | http://www.sciencedirect.com/science/article/pii/S2405654521000378 |
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