Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
Abstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this mak...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Polímeros
2019-03-01
|
Series: | Polímeros |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100410&lng=en&tlng=en |
_version_ | 1828848865921466368 |
---|---|
author | Cristiane Agra Pimentel José William de Lima Souza Flávia Suzany Ferreira dos Santos Mayelli Dantas de Sá Valéria Pereira Ferreira Gislaine Bezerra de Carvalho Barreto José Filipe Bacalhau Rodrigues Wladymyr Jefferson Bacalhau de Sousa Cláudio Orestes Britto Filho Francisco Kegenaldo Alves de Sousa Marcus Vinicius Lia Fook |
author_facet | Cristiane Agra Pimentel José William de Lima Souza Flávia Suzany Ferreira dos Santos Mayelli Dantas de Sá Valéria Pereira Ferreira Gislaine Bezerra de Carvalho Barreto José Filipe Bacalhau Rodrigues Wladymyr Jefferson Bacalhau de Sousa Cláudio Orestes Britto Filho Francisco Kegenaldo Alves de Sousa Marcus Vinicius Lia Fook |
author_sort | Cristiane Agra Pimentel |
collection | DOAJ |
description | Abstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this makes it of great importance in medicine. This study investigates a better combination of process parameters to manufacture sulfonated PEEK/HA (SPEEK/HA) membranes for biomaterials. Chemical, thermal, and biological analyses were carried out on all samples. The sulfonated structure was observed to enhance wettability, adhesion, and cell viability. Furthermore, an increase in the degree of sulfonation facilitated their workability as required for biomaterials; making them suitable for osseointegration. Besides, the SPEEK/HA membranes presented cell adhesion, confirming the viability to use as biomaterial. This study presents a cheap alternative method to easily process biomaterials of improved workability. |
first_indexed | 2024-12-12T22:38:57Z |
format | Article |
id | doaj.art-9b50072247d74b43ab0338b43ff562b7 |
institution | Directory Open Access Journal |
issn | 1678-5169 |
language | English |
last_indexed | 2024-12-12T22:38:57Z |
publishDate | 2019-03-01 |
publisher | Associação Brasileira de Polímeros |
record_format | Article |
series | Polímeros |
spelling | doaj.art-9b50072247d74b43ab0338b43ff562b72022-12-22T00:09:23ZengAssociação Brasileira de PolímerosPolímeros1678-51692019-03-0129110.1590/0104-1428.01018S0104-14282019000100410Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluationCristiane Agra PimentelJosé William de Lima SouzaFlávia Suzany Ferreira dos SantosMayelli Dantas de SáValéria Pereira FerreiraGislaine Bezerra de Carvalho BarretoJosé Filipe Bacalhau RodriguesWladymyr Jefferson Bacalhau de SousaCláudio Orestes Britto FilhoFrancisco Kegenaldo Alves de SousaMarcus Vinicius Lia FookAbstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this makes it of great importance in medicine. This study investigates a better combination of process parameters to manufacture sulfonated PEEK/HA (SPEEK/HA) membranes for biomaterials. Chemical, thermal, and biological analyses were carried out on all samples. The sulfonated structure was observed to enhance wettability, adhesion, and cell viability. Furthermore, an increase in the degree of sulfonation facilitated their workability as required for biomaterials; making them suitable for osseointegration. Besides, the SPEEK/HA membranes presented cell adhesion, confirming the viability to use as biomaterial. This study presents a cheap alternative method to easily process biomaterials of improved workability.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100410&lng=en&tlng=enbiomaterialchemical modificationhydroxyapatitemembraneSPEEK |
spellingShingle | Cristiane Agra Pimentel José William de Lima Souza Flávia Suzany Ferreira dos Santos Mayelli Dantas de Sá Valéria Pereira Ferreira Gislaine Bezerra de Carvalho Barreto José Filipe Bacalhau Rodrigues Wladymyr Jefferson Bacalhau de Sousa Cláudio Orestes Britto Filho Francisco Kegenaldo Alves de Sousa Marcus Vinicius Lia Fook Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation Polímeros biomaterial chemical modification hydroxyapatite membrane SPEEK |
title | Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation |
title_full | Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation |
title_fullStr | Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation |
title_full_unstemmed | Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation |
title_short | Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation |
title_sort | sulfonated poly ether ether ketone hydroxyapatite membrane as biomaterials process evaluation |
topic | biomaterial chemical modification hydroxyapatite membrane SPEEK |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100410&lng=en&tlng=en |
work_keys_str_mv | AT cristianeagrapimentel sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT josewilliamdelimasouza sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT flaviasuzanyferreiradossantos sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT mayellidantasdesa sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT valeriapereiraferreira sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT gislainebezerradecarvalhobarreto sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT josefilipebacalhaurodrigues sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT wladymyrjeffersonbacalhaudesousa sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT claudioorestesbrittofilho sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT franciscokegenaldoalvesdesousa sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation AT marcusviniciusliafook sulfonatedpolyetheretherketonehydroxyapatitemembraneasbiomaterialsprocessevaluation |