Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation

Abstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this mak...

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Main Authors: Cristiane Agra Pimentel, José William de Lima Souza, Flávia Suzany Ferreira dos Santos, Mayelli Dantas de Sá, Valéria Pereira Ferreira, Gislaine Bezerra de Carvalho Barreto, José Filipe Bacalhau Rodrigues, Wladymyr Jefferson Bacalhau de Sousa, Cláudio Orestes Britto Filho, Francisco Kegenaldo Alves de Sousa, Marcus Vinicius Lia Fook
Format: Article
Language:English
Published: Associação Brasileira de Polímeros 2019-03-01
Series:Polímeros
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100410&lng=en&tlng=en
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author Cristiane Agra Pimentel
José William de Lima Souza
Flávia Suzany Ferreira dos Santos
Mayelli Dantas de Sá
Valéria Pereira Ferreira
Gislaine Bezerra de Carvalho Barreto
José Filipe Bacalhau Rodrigues
Wladymyr Jefferson Bacalhau de Sousa
Cláudio Orestes Britto Filho
Francisco Kegenaldo Alves de Sousa
Marcus Vinicius Lia Fook
author_facet Cristiane Agra Pimentel
José William de Lima Souza
Flávia Suzany Ferreira dos Santos
Mayelli Dantas de Sá
Valéria Pereira Ferreira
Gislaine Bezerra de Carvalho Barreto
José Filipe Bacalhau Rodrigues
Wladymyr Jefferson Bacalhau de Sousa
Cláudio Orestes Britto Filho
Francisco Kegenaldo Alves de Sousa
Marcus Vinicius Lia Fook
author_sort Cristiane Agra Pimentel
collection DOAJ
description Abstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this makes it of great importance in medicine. This study investigates a better combination of process parameters to manufacture sulfonated PEEK/HA (SPEEK/HA) membranes for biomaterials. Chemical, thermal, and biological analyses were carried out on all samples. The sulfonated structure was observed to enhance wettability, adhesion, and cell viability. Furthermore, an increase in the degree of sulfonation facilitated their workability as required for biomaterials; making them suitable for osseointegration. Besides, the SPEEK/HA membranes presented cell adhesion, confirming the viability to use as biomaterial. This study presents a cheap alternative method to easily process biomaterials of improved workability.
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spelling doaj.art-9b50072247d74b43ab0338b43ff562b72022-12-22T00:09:23ZengAssociação Brasileira de PolímerosPolímeros1678-51692019-03-0129110.1590/0104-1428.01018S0104-14282019000100410Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluationCristiane Agra PimentelJosé William de Lima SouzaFlávia Suzany Ferreira dos SantosMayelli Dantas de SáValéria Pereira FerreiraGislaine Bezerra de Carvalho BarretoJosé Filipe Bacalhau RodriguesWladymyr Jefferson Bacalhau de SousaCláudio Orestes Britto FilhoFrancisco Kegenaldo Alves de SousaMarcus Vinicius Lia FookAbstract Poly(ether ether ketone) (PEEK) has excellent properties, such as high biocompatibility and an elastic modulus similar to bone, which makes it a suitable biomaterial. When modified with sulfuric acid (H2SO4) and hydroxyapatite (HA), its workability and bioactivity is enhanced, and this makes it of great importance in medicine. This study investigates a better combination of process parameters to manufacture sulfonated PEEK/HA (SPEEK/HA) membranes for biomaterials. Chemical, thermal, and biological analyses were carried out on all samples. The sulfonated structure was observed to enhance wettability, adhesion, and cell viability. Furthermore, an increase in the degree of sulfonation facilitated their workability as required for biomaterials; making them suitable for osseointegration. Besides, the SPEEK/HA membranes presented cell adhesion, confirming the viability to use as biomaterial. This study presents a cheap alternative method to easily process biomaterials of improved workability.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100410&lng=en&tlng=enbiomaterialchemical modificationhydroxyapatitemembraneSPEEK
spellingShingle Cristiane Agra Pimentel
José William de Lima Souza
Flávia Suzany Ferreira dos Santos
Mayelli Dantas de Sá
Valéria Pereira Ferreira
Gislaine Bezerra de Carvalho Barreto
José Filipe Bacalhau Rodrigues
Wladymyr Jefferson Bacalhau de Sousa
Cláudio Orestes Britto Filho
Francisco Kegenaldo Alves de Sousa
Marcus Vinicius Lia Fook
Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
Polímeros
biomaterial
chemical modification
hydroxyapatite
membrane
SPEEK
title Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
title_full Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
title_fullStr Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
title_full_unstemmed Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
title_short Sulfonated poly(ether ether ketone)/hydroxyapatite membrane as biomaterials: process evaluation
title_sort sulfonated poly ether ether ketone hydroxyapatite membrane as biomaterials process evaluation
topic biomaterial
chemical modification
hydroxyapatite
membrane
SPEEK
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100410&lng=en&tlng=en
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