Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis
Telomerase Cajal body protein 1 (TCAB1) is closely related to the occurrence, development and prognosis of tumors, and may affect the sensitivity of tumor radiotherapy. There are no reports about the effect of TCAB1 gene expression on proliferation and apoptosis of HEPG2 cells. We plan to investigat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-04-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2022-0096 |
| _version_ | 1797773490301960192 |
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| author | Zhang Guangmou Zhang Kefeng Yuan Meng Yuan Zhiqing |
| author_facet | Zhang Guangmou Zhang Kefeng Yuan Meng Yuan Zhiqing |
| author_sort | Zhang Guangmou |
| collection | DOAJ |
| description | Telomerase Cajal body protein 1 (TCAB1) is closely related to the occurrence, development and prognosis of tumors, and may affect the sensitivity of tumor radiotherapy. There are no reports about the effect of TCAB1 gene expression on proliferation and apoptosis of HEPG2 cells. We plan to investigate whether silencing TCAB1 using siRNA is helpful for the diagnosis and treatment of hepatocellular carcinoma. |
| first_indexed | 2024-03-12T22:07:17Z |
| format | Article |
| id | doaj.art-9b5037da19ee4d3c8fdf933b523a1199 |
| institution | Directory Open Access Journal |
| issn | 1303-829X |
| language | English |
| last_indexed | 2024-03-12T22:07:17Z |
| publishDate | 2023-04-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj.art-9b5037da19ee4d3c8fdf933b523a11992023-07-24T11:19:38ZengDe GruyterTürk Biyokimya Dergisi1303-829X2023-04-0148323924510.1515/tjb-2022-0096Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosisZhang Guangmou0Zhang Kefeng1Yuan Meng2Yuan Zhiqing3College of Life Science and Technology, Xinxiang Medical University, Xinxiang, HA, ChinaThe Third Clinical College, Xinxiang Medical University, Xinxiang, HA, ChinaThe Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, HA, ChinaSchool of Basic of Medical Sciences, Xinxiang Medical University, Xinxiang, HA, ChinaTelomerase Cajal body protein 1 (TCAB1) is closely related to the occurrence, development and prognosis of tumors, and may affect the sensitivity of tumor radiotherapy. There are no reports about the effect of TCAB1 gene expression on proliferation and apoptosis of HEPG2 cells. We plan to investigate whether silencing TCAB1 using siRNA is helpful for the diagnosis and treatment of hepatocellular carcinoma.https://doi.org/10.1515/tjb-2022-0096hepatocellular carcinomasirnatcab1telomerase |
| spellingShingle | Zhang Guangmou Zhang Kefeng Yuan Meng Yuan Zhiqing Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis Türk Biyokimya Dergisi hepatocellular carcinoma sirna tcab1 telomerase |
| title | Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis |
| title_full | Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis |
| title_fullStr | Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis |
| title_full_unstemmed | Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis |
| title_short | Silencing TCAB1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis |
| title_sort | silencing tcab1 suppresses proliferation of hepatocellular carcinoma cells by inducing apoptosis |
| topic | hepatocellular carcinoma sirna tcab1 telomerase |
| url | https://doi.org/10.1515/tjb-2022-0096 |
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