Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells
Summary Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper f...
Հիմնական հեղինակներ: | Ying Li, Hailing Hao, Evangeline Tzatzalos, Ren-Kuo Lin, Sungtae Doh, Leroy F. Liu, Yi Lisa Lyu, Li Cai |
---|---|
Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
The Company of Biologists
2014-01-01
|
Շարք: | Biology Open |
Խորագրեր: | |
Առցանց հասանելիություն: | http://bio.biologists.org/content/3/2/172 |
Նմանատիպ նյութեր
-
Retinal ganglion cells undergo cell type—specific functional changes in a computational model of cone-mediated retinal degeneration
: Aiwen Xu, և այլն
Հրապարակվել է: (2023-05-01) -
Comparing optogenetic approaches to visual restoration in a model of retinal degeneration
: Gilhooley, MJ
Հրապարակվել է: (2019) -
Ciliated, Mitochondria-Rich Postmitotic Cells are Immune-privileged, and Mimic Immunosuppressive Microenvironment of Tumor-Initiating Stem Cells: From Molecular Anatomy to Molecular Pathway
: Babak Behnam, և այլն
Հրապարակվել է: (2023-10-01) -
Developing gene therapy for inherited retinal degenerations
: Yusuf, IH
Հրապարակվել է: (2022) -
Retinal changes in an ATP-induced model of retinal degeneration
: Felix Peter Aplin, և այլն
Հրապարակվել է: (2016-04-01)