Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Summary Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper f...

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Dettagli Bibliografici
Autori principali:	Ying Li, Hailing Hao, Evangeline Tzatzalos, Ren-Kuo Lin, Sungtae Doh, Leroy F. Liu, Yi Lisa Lyu, Li Cai
Natura:	Articolo
Lingua:	English
Pubblicazione:	The Company of Biologists 2014-01-01
Serie:	Biology Open
Soggetti:	Cell survival Gene regulation Postmitotic cells Retina Top2b Transcription Retina degeneration
Accesso online:	http://bio.biologists.org/content/3/2/172

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