Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Summary Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper f...

Полное описание

Библиографические подробности
Главные авторы:	Ying Li, Hailing Hao, Evangeline Tzatzalos, Ren-Kuo Lin, Sungtae Doh, Leroy F. Liu, Yi Lisa Lyu, Li Cai
Формат:	Статья
Язык:	English
Опубликовано:	The Company of Biologists 2014-01-01
Серии:	Biology Open
Предметы:	Cell survival Gene regulation Postmitotic cells Retina Top2b Transcription Retina degeneration
Online-ссылка:	http://bio.biologists.org/content/3/2/172

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