The Inhibitory Activity of Curcumin on P-Glycoprotein and Its Uptake by and Efflux from LS180 Cells Is Not Affected by Its Galenic Formulation

The Inhibitory Activity of Curcumin on P-Glycoprotein and Its Uptake by and Efflux from LS180 Cells Is Not Affected by Its Galenic Formulation

The biological activities of curcumin in humans, including its antioxidative and anti-inflammatory functions, are limited by its naturally low bioavailability. Different formulation strategies have been developed, but the uptake of curcumin from these galenic formulations into and efflux from intest...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sandra Flory, Romina Männle, Jan Frank
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2021-11-01
Schriftenreihe:Antioxidants
Schlagworte:
cellular uptake
curcuminoids
cyclodextrin complex
drug interactions
efflux transporter
intestinal cell line
Online Zugang:https://www.mdpi.com/2076-3921/10/11/1826

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