Combined therapy with dapagliflozin and entresto offers an additional benefit on improving the heart function in rat after ischemia-reperfusion injury

Combined therapy with dapagliflozin and entresto offers an additional benefit on improving the heart function in rat after ischemia-reperfusion injury

Background: This study tested whether combined dapagliflozin and entresto treatment would be superior to either one alone for preserving the left-ventricular ejection-fraction (LVEF) in rat after ischemia-reperfusion (IR) injury. Methods: Cell culture using H9C2 cells and IR injury in rat with dapag...

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Bibliographic Details
Main Authors: Sheung-Fat Ko, Pei Hsun Sung, Chih Chao Yang, John Y. Chiang, Hon Kan Yip
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biomedical Journal
Subjects:
Ischemia-reperfusion injury
Entresto
Dapagliflozin
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417022000981

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