Inferring viral dynamics in chronically HCV infected patients from the spatial distribution of infected hepatocytes.
Chronic liver infection by hepatitis C virus (HCV) is a major public health concern. Despite partly successful treatment options, several aspects of intrahepatic HCV infection dynamics are still poorly understood, including the preferred mode of viral propagation, as well as the proportion of infect...
Main Authors: | Frederik Graw, Ashwin Balagopal, Abraham J Kandathil, Stuart C Ray, David L Thomas, Ruy M Ribeiro, Alan S Perelson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-11-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4230741?pdf=render |
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