PET Imaging of [<sup>11</sup>C]MPC-6827, a Microtubule-Based Radiotracer in Non-Human Primate Brains
Dysregulation of microtubules is commonly associated with several psychiatric and neurological disorders, including addiction and Alzheimer’s disease. Imaging of microtubules in vivo using positron emission tomography (PET) could provide valuable information on their role in the development of disea...
Main Authors: | Naresh Damuka, Paul W. Czoty, Ashley T. Davis, Michael A. Nader, Susan H. Nader, Suzanne Craft, Shannon L. Macauley, Lindsey K. Galbo, Phillip M. Epperly, Christopher T. Whitlow, April T. Davenport, Thomas J. Martin, James B. Daunais, Akiva Mintz, Kiran Kumar Solingapuram Sai |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/10/2289 |
Similar Items
-
Binding Parameters of [<sup>11</sup>C]MPC-6827, a Microtubule-Imaging PET Radiopharmaceutical in Rodents
by: Avinash H. Bansode, et al.
Published: (2023-03-01) -
Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model
by: Naresh Damuka, et al.
Published: (2022-07-01) -
Microtubule protocols /
by: Zhou, Jun
Published: (2007) -
Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation
by: Maximilian AH Jakobs, et al.
Published: (2022-10-01) -
Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases
by: Antonella Sferra, et al.
Published: (2020-10-01)