Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description
Tumor volume regression during and after chemo and radio therapy is a useful information for clinical decisions. Indeed, a quantitative, patient oriented, description of the response to treatment can guide towards the modification of the scheduled doses or the evaluation of the best time for surgery...
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Format: | Article |
Language: | English |
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MDPI AG
2022-03-01
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Series: | Journal of Personalized Medicine |
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Online Access: | https://www.mdpi.com/2075-4426/12/4/530 |
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author | Paolo Castorina Gianluca Ferini Emanuele Martorana Stefano Forte |
author_facet | Paolo Castorina Gianluca Ferini Emanuele Martorana Stefano Forte |
author_sort | Paolo Castorina |
collection | DOAJ |
description | Tumor volume regression during and after chemo and radio therapy is a useful information for clinical decisions. Indeed, a quantitative, patient oriented, description of the response to treatment can guide towards the modification of the scheduled doses or the evaluation of the best time for surgery. We propose a macroscopic algorithm which permits to follow quantitatively the time evolution of the tumor volume during and after radiochemotherapy. The method, initially validated with different cell-lines implanted in mice, is then successfully applied to the available data for partially responding and complete recovery patients. |
first_indexed | 2024-03-09T04:32:09Z |
format | Article |
id | doaj.art-9b5c800a74714399a1ce62853571e875 |
institution | Directory Open Access Journal |
issn | 2075-4426 |
language | English |
last_indexed | 2024-03-09T04:32:09Z |
publishDate | 2022-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Personalized Medicine |
spelling | doaj.art-9b5c800a74714399a1ce62853571e8752023-12-03T13:35:00ZengMDPI AGJournal of Personalized Medicine2075-44262022-03-0112453010.3390/jpm12040530Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic DescriptionPaolo Castorina0Gianluca Ferini1Emanuele Martorana2Stefano Forte3INFN, Sezione di Catania, 95123 Catania, ItalyREM Radioterapia SRL, 95029 Viagrande, ItalyIstituto Oncologico del Mediterraneo, 95029 Viagrande, ItalyIstituto Oncologico del Mediterraneo, 95029 Viagrande, ItalyTumor volume regression during and after chemo and radio therapy is a useful information for clinical decisions. Indeed, a quantitative, patient oriented, description of the response to treatment can guide towards the modification of the scheduled doses or the evaluation of the best time for surgery. We propose a macroscopic algorithm which permits to follow quantitatively the time evolution of the tumor volume during and after radiochemotherapy. The method, initially validated with different cell-lines implanted in mice, is then successfully applied to the available data for partially responding and complete recovery patients.https://www.mdpi.com/2075-4426/12/4/530oncologyradiotherapybiophysicscomplex systems |
spellingShingle | Paolo Castorina Gianluca Ferini Emanuele Martorana Stefano Forte Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description Journal of Personalized Medicine oncology radiotherapy biophysics complex systems |
title | Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description |
title_full | Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description |
title_fullStr | Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description |
title_full_unstemmed | Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description |
title_short | Tumor Volume Regression during and after Radiochemotherapy: A Macroscopic Description |
title_sort | tumor volume regression during and after radiochemotherapy a macroscopic description |
topic | oncology radiotherapy biophysics complex systems |
url | https://www.mdpi.com/2075-4426/12/4/530 |
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