Epigenetics in a Spectrum of Myeloid Diseases and Its Exploitation for Therapy

Epigenetics in a Spectrum of Myeloid Diseases and Its Exploitation for Therapy

Mutations in genes encoding chromatin regulators are early events contributing to developing asymptomatic clonal hematopoiesis of indeterminate potential and its frequent progression to myeloid diseases with increasing severity. We focus on the subset of myeloid diseases encompassing myelodysplastic...

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Bibliographic Details
Main Authors: Michael Maher, Jeannine Diesch, Marguerite-Marie Le Pannérer, Marcus Buschbeck
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
epigenetics
chromatin
epigenetic regulators
clonal hematopoiesis of indeterminate potential (CHIP)
myelodysplastic syndromes (MDS)
acute myeloid leukemia (AML)
Online Access:https://www.mdpi.com/2072-6694/13/7/1746

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