Autism in Moebius Syndrome: Comorbidity or a Coincidental State?

Pervasive developmental disorders are neuropsychiatric disorders that start in early years of life, last lifelong, and characterized by delay and abnormality in social relationship, communication, behavior and cognitive development. Moebius syndrome is a clinical condition characterized by unilatera...

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Main Authors: İbrahim Durukan, Tumer Turkbay
Format: Article
Language:English
Published: Psikiyatride Güncel Yaklaşımlar 2010-12-01
Series:Psikiyatride Güncel Yaklaşımlar
Subjects:
Online Access:http://www.cappsy.org/archives/vol2/no3/cap_02_16.pdf
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author İbrahim Durukan
Tumer Turkbay
author_facet İbrahim Durukan
Tumer Turkbay
author_sort İbrahim Durukan
collection DOAJ
description Pervasive developmental disorders are neuropsychiatric disorders that start in early years of life, last lifelong, and characterized by delay and abnormality in social relationship, communication, behavior and cognitive development. Moebius syndrome is a clinical condition characterized by unilateral or bilateral eye-face palsy associated with muscle or bone malformations in the upper or lower limbs. Most accepted clinical criteria to characterize the sequence are the involvement of the VI and VII cranial nerves. Though some authors suggest a causal relationship between autism and some medical conditions, to draw such result is quite complicated and difficult. Case reports and articles draw attention to the comorbidity of autism in Moebius syndrome. Despite arguments favoring a strong relationship between autism and Moebius syndrome, some questions about this relationship are still left unanswered and controversial. There are some research findings suggesting higher prevalence of autism among patients with Moebius syndrome, however some others did not report an increase in autism prevalence in Moebius syndrome. Clinical features of Moebius syndrome comprise difficulties in making diagnosis of autism. Long term follow-up of larger number of cases are necessary to understand whether the presence of both autism and Moebius syndrome in a patient represents comorbidity or only a coincidental condition.
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spelling doaj.art-9b5e13f4f7f14dad8418431a1a65d2342024-02-03T05:54:42ZengPsikiyatride Güncel YaklaşımlarPsikiyatride Güncel Yaklaşımlar1309-06581309-06742010-12-0123308317Autism in Moebius Syndrome: Comorbidity or a Coincidental State?İbrahim DurukanTumer TurkbayPervasive developmental disorders are neuropsychiatric disorders that start in early years of life, last lifelong, and characterized by delay and abnormality in social relationship, communication, behavior and cognitive development. Moebius syndrome is a clinical condition characterized by unilateral or bilateral eye-face palsy associated with muscle or bone malformations in the upper or lower limbs. Most accepted clinical criteria to characterize the sequence are the involvement of the VI and VII cranial nerves. Though some authors suggest a causal relationship between autism and some medical conditions, to draw such result is quite complicated and difficult. Case reports and articles draw attention to the comorbidity of autism in Moebius syndrome. Despite arguments favoring a strong relationship between autism and Moebius syndrome, some questions about this relationship are still left unanswered and controversial. There are some research findings suggesting higher prevalence of autism among patients with Moebius syndrome, however some others did not report an increase in autism prevalence in Moebius syndrome. Clinical features of Moebius syndrome comprise difficulties in making diagnosis of autism. Long term follow-up of larger number of cases are necessary to understand whether the presence of both autism and Moebius syndrome in a patient represents comorbidity or only a coincidental condition.http://www.cappsy.org/archives/vol2/no3/cap_02_16.pdfMoebius SyndromeAutismComorbidity
spellingShingle İbrahim Durukan
Tumer Turkbay
Autism in Moebius Syndrome: Comorbidity or a Coincidental State?
Psikiyatride Güncel Yaklaşımlar
Moebius Syndrome
Autism
Comorbidity
title Autism in Moebius Syndrome: Comorbidity or a Coincidental State?
title_full Autism in Moebius Syndrome: Comorbidity or a Coincidental State?
title_fullStr Autism in Moebius Syndrome: Comorbidity or a Coincidental State?
title_full_unstemmed Autism in Moebius Syndrome: Comorbidity or a Coincidental State?
title_short Autism in Moebius Syndrome: Comorbidity or a Coincidental State?
title_sort autism in moebius syndrome comorbidity or a coincidental state
topic Moebius Syndrome
Autism
Comorbidity
url http://www.cappsy.org/archives/vol2/no3/cap_02_16.pdf
work_keys_str_mv AT ibrahimdurukan autisminmoebiussyndromecomorbidityoracoincidentalstate
AT tumerturkbay autisminmoebiussyndromecomorbidityoracoincidentalstate