Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice
Abstract Reactive oxygen species (ROS) can induce oxidative injury and are generally regarded as toxic byproducts, although they are increasingly recognized for their signaling functions. Increased ROS often accompanies liver regeneration (LR) after liver injuries, however, their role in LR and the...
Main Authors: | Hua Bai, Cong-Wen Fang, Ying Shi, Song Zhai, An Jiang, Ying-Na Li, Lin Wang, Qi-Ling Liu, Geng-Yao Zhou, Jia-Hao Cao, Jia Li, Xue-Kang Yang, Xu-Jun Qin |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-03-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05744-w |
Similar Items
-
FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes
by: Chi-Qian Liang, et al.
Published: (2022-06-01) -
Role of FoxO1 in acne and effect of isotretinoin on FoxO1 expression
by: Parul Kamboj, et al.
Published: (2024-01-01) -
Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis
by: Sufang Zhong, et al.
Published: (2023-07-01) -
Autophagy mediated by ROS-AKT-FoxO pathway is required for intestinal regeneration in echinoderms
by: Chuili Zeng, et al.
Published: (2025-01-01) -
FoxO Proteins in the Nervous System
by: Kenneth Maiese
Published: (2015-01-01)