Synthesis, molecular modelling and biological evaluation of new 4-aminothiophene and thienopyrimidine compounds
A series of 4-amino-5-substituted-thiophene derivatives 3, 5 and 7, along with their corresponding thieno[3,2-d]pyrimidine compounds 4, 6 and 8, were synthesized and characterized. DFT calculations were utilized to determine frontier orbitals energies. The data showed that the compounds have low HOM...
Main Authors: | Aisha Hossan, Mansoor Alsahag, Ali Alisaac, Majid A. Bamaga, Adel I. Alalawy, Nashwa M. El-Metwaly |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
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Series: | Journal of Taibah University for Science |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/16583655.2023.2164993 |
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