NINJ1 Regulates Platelet Activation and PANoptosis in Septic Disseminated Intravascular Coagulation
Disseminated intravascular coagulation (DIC), which is closely related to platelet activation, is a key factor leading to high mortality in sepsis. The release of contents from plasma membrane rupture after platelet death further aggravates thrombosis. Nerve injury-induced protein 1 (NINJ1) is a cel...
Main Authors: | Xiaoli Zhou, Xiuxian Yu, Chengyu Wan, Fan Li, Yilan Wang, Kun Zhang, Lijuan Feng, Ao Wen, Jiangrong Deng, Shiyi Li, Guang Xin, Wen Huang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/4/4168 |
Similar Items
-
Dysmyelination by Oligodendrocyte‐Specific Ablation of Ninj2 Contributes to Depressive‐Like Behaviors
by: Yuxia Sun, et al.
Published: (2022-01-01) -
Role of NINJ1 in Gout Flare and Potential as a Drug Target
by: Zhang H, et al.
Published: (2022-09-01) -
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
by: Jazlyn P Borges, et al.
Published: (2022-12-01) -
PANoptosis: Mechanism and Role in Pulmonary Diseases
by: Shiyi Chen, et al.
Published: (2023-10-01) -
Genetic polymorphisms of MRPS30-DT and NINJ2 may influence lung cancer risk
by: Yan Shouchun, et al.
Published: (2023-03-01)