Recent Advances in the Therapeutic Efficacy of Artesunate
Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and viruses. It also exhibits antidiabetic, anti-inflammatory,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/14/3/504 |
| _version_ | 1797443641830014976 |
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| author | Ngonidzashe Ruwizhi Rejoice Bethusile Maseko Blessing Atim Aderibigbe |
| author_facet | Ngonidzashe Ruwizhi Rejoice Bethusile Maseko Blessing Atim Aderibigbe |
| author_sort | Ngonidzashe Ruwizhi |
| collection | DOAJ |
| description | Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and viruses. It also exhibits antidiabetic, anti-inflammatory, anti-atherosclerosis, immunosuppressive activities, etc. During its administration, artesunate can be loaded in liposomes, alone or in combination with other therapeutic agents. Administration routes include intragastrical, intravenous, oral, and parenteral. The biological activity of artesunate is based on its ability to regulate some biological pathways. This manuscript reports a critical review of the recent advances in the therapeutic efficacy of artesunate. |
| first_indexed | 2024-03-09T13:00:01Z |
| format | Article |
| id | doaj.art-9b652023951141dba6c1fc907fd70bf3 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-09T13:00:01Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-9b652023951141dba6c1fc907fd70bf32023-11-30T21:55:50ZengMDPI AGPharmaceutics1999-49232022-02-0114350410.3390/pharmaceutics14030504Recent Advances in the Therapeutic Efficacy of ArtesunateNgonidzashe Ruwizhi0Rejoice Bethusile Maseko1Blessing Atim Aderibigbe2Department of Chemistry, University of Fort Hare, Alice Campus, Alice, Eastern Cape 5700, South AfricaDepartment of Chemistry, School of Science and Technology, Sefako Makgatho Health Sciences University, Ga-Rankuwa 0208, South AfricaDepartment of Chemistry, University of Fort Hare, Alice Campus, Alice, Eastern Cape 5700, South AfricaArtesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and viruses. It also exhibits antidiabetic, anti-inflammatory, anti-atherosclerosis, immunosuppressive activities, etc. During its administration, artesunate can be loaded in liposomes, alone or in combination with other therapeutic agents. Administration routes include intragastrical, intravenous, oral, and parenteral. The biological activity of artesunate is based on its ability to regulate some biological pathways. This manuscript reports a critical review of the recent advances in the therapeutic efficacy of artesunate.https://www.mdpi.com/1999-4923/14/3/504artesunatemalariaanticancertumourantiviralCOVID-19 |
| spellingShingle | Ngonidzashe Ruwizhi Rejoice Bethusile Maseko Blessing Atim Aderibigbe Recent Advances in the Therapeutic Efficacy of Artesunate Pharmaceutics artesunate malaria anticancer tumour antiviral COVID-19 |
| title | Recent Advances in the Therapeutic Efficacy of Artesunate |
| title_full | Recent Advances in the Therapeutic Efficacy of Artesunate |
| title_fullStr | Recent Advances in the Therapeutic Efficacy of Artesunate |
| title_full_unstemmed | Recent Advances in the Therapeutic Efficacy of Artesunate |
| title_short | Recent Advances in the Therapeutic Efficacy of Artesunate |
| title_sort | recent advances in the therapeutic efficacy of artesunate |
| topic | artesunate malaria anticancer tumour antiviral COVID-19 |
| url | https://www.mdpi.com/1999-4923/14/3/504 |
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