Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice

Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice

The potential of levosulpiride-loaded nanostructured lipid carriers (LSP-NLCs) for enhanced antidepressant and anxiolytic effects was evaluated in the current study. A forced swim test (FST) and tail suspension test (TST) were carried out to determine the antidepressant effect whereas anxiolytic act...

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Bibliographic Details
Main Authors: Sadia Tabassam Arif, Muhammad Ayub Khan, Shahiq uz Zaman, Hafiz Shoaib Sarwar, Abida Raza, Muhammad Sarfraz, Yousef A. Bin Jardan, Muhammad Umair Amin, Muhammad Farhan Sohail
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceuticals
Subjects:
levosulpiride
antidepressant
nanostructured lipid carriers
acute toxicity
in vivo imaging
Online Access:https://www.mdpi.com/1424-8247/16/9/1220

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