Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation

Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation

Objective: Recent WHO 2017 guidelines mandates mutational analysis for the diagnosis of myeloproliferative disorders (MPN). JAK2V617F has been found in only 50-60% of Primary myelofibrosis (PMF) and Essential thrombocythaemia (ET). A recently discovered somatic Calreticulin (CALR) mutation has been...

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Bibliographic Details
Main Authors: Sanjeet ROY, Marie Therese MANIPADAM, Poonkuzhali BALASUBRAMANIAN
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2022-01-01
Series:Türk Patoloji Dergisi
Subjects:
immunohistochemistry
cal2
calreticulin
myeloproliferative neoplasm
calr
Online Access: http://www.turkjpath.org/pdf.php3?id=1988

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