Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report
Abstract Background Persistent hyperplastic primary vitreous (PHPV) is a rare congenital developmental ocular disorder caused by incomplete regression of the embryonic hyaloid vasculature. Here we report a case of nonsurgical unilateral anterior PHPV that was managed by amblyopia treatment and resul...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-07-01
|
| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12886-019-1173-3 |
| _version_ | 1818693508588896256 |
|---|---|
| author | Jianqing Li Jiaju Zhang Peirong Lu |
| author_facet | Jianqing Li Jiaju Zhang Peirong Lu |
| author_sort | Jianqing Li |
| collection | DOAJ |
| description | Abstract Background Persistent hyperplastic primary vitreous (PHPV) is a rare congenital developmental ocular disorder caused by incomplete regression of the embryonic hyaloid vasculature. Here we report a case of nonsurgical unilateral anterior PHPV that was managed by amblyopia treatment and resulted in an improvement of visual acuity and regression of the fetal vasculature. Case presentation A three-year-old girl was diagnosed with unilateral anterior PHPV in the left eye, manifested with posterior pole cataract, posterior capsule opacification, tunica vasculosa lentis, and a floating hyaloid artery connected to the retrolental mass. The plaque was not large enough to fill the pupil, and conservative management along with amblyopia treatment was conducted. Nineteen months later, the visual acuity in the affected eye improved from 20/100 to 20/50 with correction, and the fetal vasculature regressed gradually and finally into a nonperfusion ghost vessel. Conclusions In PHPV-affected children, regression of the fetal vasculature may be observed, and conservative management and amblyopia treatment may be helpful for visual improvement. |
| first_indexed | 2024-12-17T13:14:48Z |
| format | Article |
| id | doaj.art-9b6f98d3272d4f059190f6962496be47 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-17T13:14:48Z |
| publishDate | 2019-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-9b6f98d3272d4f059190f6962496be472022-12-21T21:47:01ZengBMCBMC Ophthalmology1471-24152019-07-011911510.1186/s12886-019-1173-3Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case reportJianqing Li0Jiaju Zhang1Peirong Lu2Department of Ophthalmology, the First Affiliated Hospital of Soochow UniversityDepartment of Ophthalmology, the First Affiliated Hospital of Soochow UniversityDepartment of Ophthalmology, the First Affiliated Hospital of Soochow UniversityAbstract Background Persistent hyperplastic primary vitreous (PHPV) is a rare congenital developmental ocular disorder caused by incomplete regression of the embryonic hyaloid vasculature. Here we report a case of nonsurgical unilateral anterior PHPV that was managed by amblyopia treatment and resulted in an improvement of visual acuity and regression of the fetal vasculature. Case presentation A three-year-old girl was diagnosed with unilateral anterior PHPV in the left eye, manifested with posterior pole cataract, posterior capsule opacification, tunica vasculosa lentis, and a floating hyaloid artery connected to the retrolental mass. The plaque was not large enough to fill the pupil, and conservative management along with amblyopia treatment was conducted. Nineteen months later, the visual acuity in the affected eye improved from 20/100 to 20/50 with correction, and the fetal vasculature regressed gradually and finally into a nonperfusion ghost vessel. Conclusions In PHPV-affected children, regression of the fetal vasculature may be observed, and conservative management and amblyopia treatment may be helpful for visual improvement.http://link.springer.com/article/10.1186/s12886-019-1173-3Persistent hyperplastic primary vitreousPersistent fetal vasculatureCongenital cataractTunica vasculosa lentisAmblyopia |
| spellingShingle | Jianqing Li Jiaju Zhang Peirong Lu Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report BMC Ophthalmology Persistent hyperplastic primary vitreous Persistent fetal vasculature Congenital cataract Tunica vasculosa lentis Amblyopia |
| title | Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report |
| title_full | Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report |
| title_fullStr | Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report |
| title_full_unstemmed | Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report |
| title_short | Regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous: a case report |
| title_sort | regression of fetal vasculature and visual improvement in nonsurgical persistent hyperplastic primary vitreous a case report |
| topic | Persistent hyperplastic primary vitreous Persistent fetal vasculature Congenital cataract Tunica vasculosa lentis Amblyopia |
| url | http://link.springer.com/article/10.1186/s12886-019-1173-3 |
| work_keys_str_mv | AT jianqingli regressionoffetalvasculatureandvisualimprovementinnonsurgicalpersistenthyperplasticprimaryvitreousacasereport AT jiajuzhang regressionoffetalvasculatureandvisualimprovementinnonsurgicalpersistenthyperplasticprimaryvitreousacasereport AT peironglu regressionoffetalvasculatureandvisualimprovementinnonsurgicalpersistenthyperplasticprimaryvitreousacasereport |