Sleep and Healthy Aging Research on Depression (SHARE-D) randomized controlled trial: Protocol overview of an experimental model of depression with insomnia, inflammation, and affect mechanisms in older adults

Sleep and Healthy Aging Research on Depression (SHARE-D) randomized controlled trial: Protocol overview of an experimental model of depression with insomnia, inflammation, and affect mechanisms in older adults

Depression, one of the most common diseases in older adults, carries significant risk for morbidity and mortality. Because of the burgeoning population of older adults, the enormous burden of late-life depression, and the limited efficacy of current antidepressants in older adults, biologically plau...

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Bibliographic Details
Main Authors: Michael R. Irwin, Chloe C. Boyle, Joshua H. Cho, Dominique Piber, Elizabeth C. Breen, Nina Sadeghi, Daisy Castillo, Michael Smith, Naomi I. Eisenberger, Richard Olmstead
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Depression
Insomnia
Inflammation
Aging
Human subjects
Clinical trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354623000157

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