Distinct immune composition in lymph node and peripheral blood of CLL patients is reshaped during venetoclax treatment

Distinct immune composition in lymph node and peripheral blood of CLL patients is reshaped during venetoclax treatment

Abstract: Morbidity and mortality due to immunosuppression remain among the foremost clinical challenges in chronic lymphocytic leukemia (CLL). Although immunosuppression is considered to originate within the lymph node (LN) microenvironment, alterations in T and natural killer (NK) cells have almos...

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Main Authors: Iris de Weerdt, Tom Hofland, Renate de Boer, Johan A. Dobber, Julie Dubois, Denise van Nieuwenhuize, Mehrdad Mobasher, Fransien de Boer, Mels Hoogendoorn, Gerjo A. Velders, Marjolein van der Klift, Ester B.M. Remmerswaal, Frederike J. Bemelman, Carsten U. Niemann, Sabina Kersting, Mark-David Levin, Eric Eldering, Sanne H. Tonino, Arnon P. Kater
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S247395292030015X

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http://www.sciencedirect.com/science/article/pii/S247395292030015X

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