Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study
The effects of the coronavirus disease 2019 (COVID-19) pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors, through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter. Early st...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Asian Journal of Andrology |
| Subjects: | |
| Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=2;spage=240;epage=244;aulast=Kumar |
| _version_ | 1797866790688129024 |
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| author | Tribhuwan Kumar Kamlesh Jha Md Zabihullah Kumari Neelu Yogesh Kumar Kumar Siddharth |
| author_facet | Tribhuwan Kumar Kamlesh Jha Md Zabihullah Kumari Neelu Yogesh Kumar Kumar Siddharth |
| author_sort | Tribhuwan Kumar |
| collection | DOAJ |
| description | The effects of the coronavirus disease 2019 (COVID-19) pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors, through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter. Early studies showed decreases in semen quality during and after recovery from COVID-19. However, no semen quality studies have examined the effects of widespread subclinical and mild disease, as well as changes in lifestyle, psychosocial behavior, intake of dietary supplements, and stress. This cross-sectional study compared semen quality parameters in male partners of infertile couples between men who underwent semen analysis before the COVID-19 pandemic (prepandemic group) and men who underwent semen analysis during the pandemic period (pandemic group); the analysis sought to clarify the overall effects of the pandemic. No participants in the pandemic group had experienced clinically overt disease. Among the 239 participants, mean body weight (P = 0.001), mean body mass index (P < 0.001), median sperm concentration (P = 0.014), total sperm count (P = 0.006), and total percentages of motile (P = 0.013) and abnormal cells (P < 0.001) were significantly greater in the pandemic group (n = 137) than those in the prepandemic group (n = 102). Among abnormal cells, the percentages of cells with excess residual cytoplasm (P < 0.001), head defects (P < 0.001), and tail defects (P = 0.015) were significantly greater in the pandemic group than those in the prepandemic group. With the exception of morphology, the overall semenogram results were better in the pandemic group than those in the prepandemic group. |
| first_indexed | 2024-04-09T23:29:54Z |
| format | Article |
| id | doaj.art-9b713a64f3114adebfa50134a0b38d8d |
| institution | Directory Open Access Journal |
| issn | 1008-682X 1745-7262 |
| language | English |
| last_indexed | 2024-04-09T23:29:54Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj.art-9b713a64f3114adebfa50134a0b38d8d2023-03-21T07:26:14ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622023-01-0125224024410.4103/aja202278Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational studyTribhuwan KumarKamlesh JhaMd ZabihullahKumari NeeluYogesh KumarKumar SiddharthThe effects of the coronavirus disease 2019 (COVID-19) pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors, through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter. Early studies showed decreases in semen quality during and after recovery from COVID-19. However, no semen quality studies have examined the effects of widespread subclinical and mild disease, as well as changes in lifestyle, psychosocial behavior, intake of dietary supplements, and stress. This cross-sectional study compared semen quality parameters in male partners of infertile couples between men who underwent semen analysis before the COVID-19 pandemic (prepandemic group) and men who underwent semen analysis during the pandemic period (pandemic group); the analysis sought to clarify the overall effects of the pandemic. No participants in the pandemic group had experienced clinically overt disease. Among the 239 participants, mean body weight (P = 0.001), mean body mass index (P < 0.001), median sperm concentration (P = 0.014), total sperm count (P = 0.006), and total percentages of motile (P = 0.013) and abnormal cells (P < 0.001) were significantly greater in the pandemic group (n = 137) than those in the prepandemic group (n = 102). Among abnormal cells, the percentages of cells with excess residual cytoplasm (P < 0.001), head defects (P < 0.001), and tail defects (P = 0.015) were significantly greater in the pandemic group than those in the prepandemic group. With the exception of morphology, the overall semenogram results were better in the pandemic group than those in the prepandemic group.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=2;spage=240;epage=244;aulast=Kumarcoronavirus disease 2019 pandemic; male infertility; sars-cov-2; semen analysis |
| spellingShingle | Tribhuwan Kumar Kamlesh Jha Md Zabihullah Kumari Neelu Yogesh Kumar Kumar Siddharth Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study Asian Journal of Andrology coronavirus disease 2019 pandemic; male infertility; sars-cov-2; semen analysis |
| title | Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study |
| title_full | Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study |
| title_fullStr | Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study |
| title_full_unstemmed | Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study |
| title_short | Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospital-based observational study |
| title_sort | effects of the covid 19 pandemic on semen quality in male partners of infertile couples a hospital based observational study |
| topic | coronavirus disease 2019 pandemic; male infertility; sars-cov-2; semen analysis |
| url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=2;spage=240;epage=244;aulast=Kumar |
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