Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management
The presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the different...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-03-01
|
| Series: | JPRAS Open |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352587818300329 |
| _version_ | 1819100608748060672 |
|---|---|
| author | Isadora Morone Guilherme Pansardi de Andrade Paola Soares Cardoso Afrânio Coelho de Oliveira Flávia Clímaco João Medeiros Diogo Franco |
| author_facet | Isadora Morone Guilherme Pansardi de Andrade Paola Soares Cardoso Afrânio Coelho de Oliveira Flávia Clímaco João Medeiros Diogo Franco |
| author_sort | Isadora Morone |
| collection | DOAJ |
| description | The presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the differential diagnosis must be between juvenile fibroadenomatosis, phyllodes tumours and other even less common diseases of the mammary gland, such as Pseudoangiomatous Stromal Hyperplasia (PASH). This is caused by the exacerbated proliferation of mature fibroblasts and myofibroblasts, with the trigger factor still unknown. This study reports on a rare case of bilateral PASH in a young patient, describing its diagnosis and the surgical technique used. Keywords: Pseudoangiomatous stromal hyperplasia, PASH, Breast, Angiosarcoma |
| first_indexed | 2024-12-22T01:05:29Z |
| format | Article |
| id | doaj.art-9b727c0182d14444bddebce3989161aa |
| institution | Directory Open Access Journal |
| issn | 2352-5878 |
| language | English |
| last_indexed | 2024-12-22T01:05:29Z |
| publishDate | 2019-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JPRAS Open |
| spelling | doaj.art-9b727c0182d14444bddebce3989161aa2022-12-21T18:44:06ZengElsevierJPRAS Open2352-58782019-03-0119106110Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and managementIsadora Morone0Guilherme Pansardi de Andrade1Paola Soares Cardoso2Afrânio Coelho de Oliveira3Flávia Clímaco4João Medeiros5Diogo Franco6Corresponding author.; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), BrazilThe presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the differential diagnosis must be between juvenile fibroadenomatosis, phyllodes tumours and other even less common diseases of the mammary gland, such as Pseudoangiomatous Stromal Hyperplasia (PASH). This is caused by the exacerbated proliferation of mature fibroblasts and myofibroblasts, with the trigger factor still unknown. This study reports on a rare case of bilateral PASH in a young patient, describing its diagnosis and the surgical technique used. Keywords: Pseudoangiomatous stromal hyperplasia, PASH, Breast, Angiosarcomahttp://www.sciencedirect.com/science/article/pii/S2352587818300329 |
| spellingShingle | Isadora Morone Guilherme Pansardi de Andrade Paola Soares Cardoso Afrânio Coelho de Oliveira Flávia Clímaco João Medeiros Diogo Franco Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management JPRAS Open |
| title | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
| title_full | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
| title_fullStr | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
| title_full_unstemmed | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
| title_short | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
| title_sort | bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia a challenge in reconstruction and management |
| url | http://www.sciencedirect.com/science/article/pii/S2352587818300329 |
| work_keys_str_mv | AT isadoramorone bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement AT guilhermepansardideandrade bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement AT paolasoarescardoso bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement AT afraniocoelhodeoliveira bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement AT flaviaclimaco bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement AT joaomedeiros bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement AT diogofranco bilateralpseudoangiomatousstromalhyperplasiainchildhoodgigantomastiaachallengeinreconstructionandmanagement |