Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens
Synbiotics can prevent gastrointestinal infections in broilers. This work studies the effect of a Synbiotic on broilers. One-day-old male broilers were divided into groups: Control; Synbiotic; Synbiotic + <i>S</i>. Typhimurium; Synbiotic + <i>C. perfringens</i>; Synbiotic + &...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/9/10/777 |
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| author | Zuamí Villagrán-de la Mora Karla Nuño Olga Vázquez-Paulino Hugo Avalos Javier Castro-Rosas Carlos Gómez-Aldapa Carlos Angulo Felipe Ascencio Angélica Villarruel-López |
| author_facet | Zuamí Villagrán-de la Mora Karla Nuño Olga Vázquez-Paulino Hugo Avalos Javier Castro-Rosas Carlos Gómez-Aldapa Carlos Angulo Felipe Ascencio Angélica Villarruel-López |
| author_sort | Zuamí Villagrán-de la Mora |
| collection | DOAJ |
| description | Synbiotics can prevent gastrointestinal infections in broilers. This work studies the effect of a Synbiotic on broilers. One-day-old male broilers were divided into groups: Control; Synbiotic; Synbiotic + <i>S</i>. Typhimurium; Synbiotic + <i>C. perfringens</i>; Synbiotic + <i>S</i>. Typhimurium + <i>C. perfringens</i>; <i>S</i>. Typhimurium; <i>C. perfringens</i>; and <i>S</i>. Typhimurium + <i>C. perfringens</i>. Histopathological analysis revealed that the Synbiotic promoted longer villi, less deep crypts, and better villi-crypt ratio. Broilers treated with the Synbiotic, infected with pathogens or not, had healthier mucosa. In groups infected with pathogens, the frequency and intensity of histopathologic lesions were lessened often in groups treated with the Synbiotic. The Synbiotic group had higher lactic acid bacteria counts than the Control group on day 39, and the isolation frequency of <i>S</i>. Typhimurium was lower (<i>p</i> < 0.05) in the Synbiotic-treated groups. On day 18, mucosa, villi, villi-crypt ratio, crypt, and feed intake were influenced by <i>Enterobacteriaceae</i>. However, on day 39 (end of the trial), those parameters were influenced by lactic acid bacteria. The Synbiotic influenced morphological modifications in the duodenal mucosa, which in turn gave the broilers the ability to resist infections caused by <i>S</i>. Typhimurium and <i>C. perfringens</i>, by inhibiting their growth and decreasing the intensity and frequency of histopathological injuries. |
| first_indexed | 2024-12-21T15:30:20Z |
| format | Article |
| id | doaj.art-9b72d0cb30e04be4946e4f7de6aa65eb |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-12-21T15:30:20Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-9b72d0cb30e04be4946e4f7de6aa65eb2022-12-21T18:58:46ZengMDPI AGAnimals2076-26152019-10-0191077710.3390/ani9100777ani9100777Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler ChickensZuamí Villagrán-de la Mora0Karla Nuño1Olga Vázquez-Paulino2Hugo Avalos3Javier Castro-Rosas4Carlos Gómez-Aldapa5Carlos Angulo6Felipe Ascencio7Angélica Villarruel-López8Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Av. Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur 23096 La Paz, BCS, MexicoDepartamento de Ciencias Biomédicas, Centro Universitario de Tonalá, Universidad de Guadalajara, Nuevo Perif. Ote. 555, Ejido San José, Tateposco 45425 Tonalá, Jalisco, MexicoDepartamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Blvd. Gral. Marcelino García Barragán 1421, Olímpica 44430, Guadalajara, Jalisco, MexicoDepartamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Blvd. Gral. Marcelino García Barragán 1421, Olímpica 44430, Guadalajara, Jalisco, MexicoÁrea Académica de Química, Instituto de Ciencias Básicas e Ingeniería, Ciudad del Conocimiento, Universidad Autónoma del Estado de Hidalgo, Abasolo 600, Centro 42000, Pachuca de Soto, Hidalgo, MexicoÁrea Académica de Química, Instituto de Ciencias Básicas e Ingeniería, Ciudad del Conocimiento, Universidad Autónoma del Estado de Hidalgo, Abasolo 600, Centro 42000, Pachuca de Soto, Hidalgo, MexicoCentro de Investigaciones Biológicas del Noroeste (CIBNOR), Av. Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur 23096 La Paz, BCS, MexicoCentro de Investigaciones Biológicas del Noroeste (CIBNOR), Av. Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur 23096 La Paz, BCS, MexicoDepartamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Blvd. Gral. Marcelino García Barragán 1421, Olímpica 44430, Guadalajara, Jalisco, MexicoSynbiotics can prevent gastrointestinal infections in broilers. This work studies the effect of a Synbiotic on broilers. One-day-old male broilers were divided into groups: Control; Synbiotic; Synbiotic + <i>S</i>. Typhimurium; Synbiotic + <i>C. perfringens</i>; Synbiotic + <i>S</i>. Typhimurium + <i>C. perfringens</i>; <i>S</i>. Typhimurium; <i>C. perfringens</i>; and <i>S</i>. Typhimurium + <i>C. perfringens</i>. Histopathological analysis revealed that the Synbiotic promoted longer villi, less deep crypts, and better villi-crypt ratio. Broilers treated with the Synbiotic, infected with pathogens or not, had healthier mucosa. In groups infected with pathogens, the frequency and intensity of histopathologic lesions were lessened often in groups treated with the Synbiotic. The Synbiotic group had higher lactic acid bacteria counts than the Control group on day 39, and the isolation frequency of <i>S</i>. Typhimurium was lower (<i>p</i> < 0.05) in the Synbiotic-treated groups. On day 18, mucosa, villi, villi-crypt ratio, crypt, and feed intake were influenced by <i>Enterobacteriaceae</i>. However, on day 39 (end of the trial), those parameters were influenced by lactic acid bacteria. The Synbiotic influenced morphological modifications in the duodenal mucosa, which in turn gave the broilers the ability to resist infections caused by <i>S</i>. Typhimurium and <i>C. perfringens</i>, by inhibiting their growth and decreasing the intensity and frequency of histopathological injuries.https://www.mdpi.com/2076-2615/9/10/777concurrent colonizationprobioticprebioticbroiler<i>salmonella</i> typhimurium<i>clostridium perfringens</i>intestinal mucosa |
| spellingShingle | Zuamí Villagrán-de la Mora Karla Nuño Olga Vázquez-Paulino Hugo Avalos Javier Castro-Rosas Carlos Gómez-Aldapa Carlos Angulo Felipe Ascencio Angélica Villarruel-López Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens Animals concurrent colonization probiotic prebiotic broiler <i>salmonella</i> typhimurium <i>clostridium perfringens</i> intestinal mucosa |
| title | Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens |
| title_full | Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens |
| title_fullStr | Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens |
| title_full_unstemmed | Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens |
| title_short | Effect of a Synbiotic Mix on Intestinal Structural Changes, and <i>Salmonella</i> Typhimurium and <i>Clostridium Perfringens</i> Colonization in Broiler Chickens |
| title_sort | effect of a synbiotic mix on intestinal structural changes and i salmonella i typhimurium and i clostridium perfringens i colonization in broiler chickens |
| topic | concurrent colonization probiotic prebiotic broiler <i>salmonella</i> typhimurium <i>clostridium perfringens</i> intestinal mucosa |
| url | https://www.mdpi.com/2076-2615/9/10/777 |
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