Soft Biomimetic Approach for the Development of Calcinosis-Resistant Glutaraldehyde-Fixed Biomaterials for Cardiovascular Surgery

Soft Biomimetic Approach for the Development of Calcinosis-Resistant Glutaraldehyde-Fixed Biomaterials for Cardiovascular Surgery

Pathological aseptic calcification is the most common form of structural valvular degeneration (SVD), leading to premature failure of heart valve bioprostheses (BHVs). The processing methods used to obtain GA-fixed pericardium-based biomaterials determine the hemodynamic characteristics and durabili...

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Bibliographic Details
Main Authors: Alyona I. Zvyagina, Vladislav V. Minaychev, Margarita I. Kobyakova, Yana V. Lomovskaya, Anatoliy S. Senotov, Kira V. Pyatina, Vladimir S. Akatov, Roman S. Fadeev, Irina S. Fadeeva
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomimetics
Subjects:
structural valve degeneration
matrix damage
glutaraldehyde-fixed biomaterials
pericardium
immunogenicity
calcification
Online Access:https://www.mdpi.com/2313-7673/8/4/357

Internet

https://www.mdpi.com/2313-7673/8/4/357

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