CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy

AIM:To investigate computed tomography (CT) features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy (TAO). METHODS:A total of605 eyes of 325 patients with exophthalmos due to TAO were classified as grade I (mild exophthalmos) or II (severe exophthalmos) based on orb...

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Main Authors: Wei-Min He, Jenny Y. Zhang, Zhi-Jia Fang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2013-04-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633750/
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author Wei-Min He
Jenny Y. Zhang
Zhi-Jia Fang
author_facet Wei-Min He
Jenny Y. Zhang
Zhi-Jia Fang
author_sort Wei-Min He
collection DOAJ
description AIM:To investigate computed tomography (CT) features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy (TAO). METHODS:A total of605 eyes of 325 patients with exophthalmos due to TAO were classified as grade I (mild exophthalmos) or II (severe exophthalmos) based on orbital CT imaging. The increased orbital volume features, such as changes from extraocular muscles, orbital fat, or both, were analyzed. RESULTS: A total of 605 eyes were analyzed, among them 62.98% presented grade I exophthalmos, while 36.02% showed grade II exophthalmos.#$TAB In grade I, 56.69% showed orbital fat change, and in grade II, 89.29% exhibited extraocular muscle enlargement. CONCLUSION: Orbital fat and extraocular muscle enlargement are likely to be observed on CTs of subjects with mild and severe exophthalmos, respectively. Our results suggest that CT findings may guide TAO clinical therapy recommendations and prognosis.
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spelling doaj.art-9b7e4a07533144ac8da92937ee9dde672022-12-22T02:47:30ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982013-04-016214614910.3980/j.issn.2222-3959.2013.02.07CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathyWei-Min HeJenny Y. ZhangZhi-Jia FangAIM:To investigate computed tomography (CT) features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy (TAO). METHODS:A total of605 eyes of 325 patients with exophthalmos due to TAO were classified as grade I (mild exophthalmos) or II (severe exophthalmos) based on orbital CT imaging. The increased orbital volume features, such as changes from extraocular muscles, orbital fat, or both, were analyzed. RESULTS: A total of 605 eyes were analyzed, among them 62.98% presented grade I exophthalmos, while 36.02% showed grade II exophthalmos.#$TAB In grade I, 56.69% showed orbital fat change, and in grade II, 89.29% exhibited extraocular muscle enlargement. CONCLUSION: Orbital fat and extraocular muscle enlargement are likely to be observed on CTs of subjects with mild and severe exophthalmos, respectively. Our results suggest that CT findings may guide TAO clinical therapy recommendations and prognosis.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633750/thyroid-associated ophthalmopathy (TAO)computed tomography (CT)exophthalmos
spellingShingle Wei-Min He
Jenny Y. Zhang
Zhi-Jia Fang
CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy
International Journal of Ophthalmology
thyroid-associated ophthalmopathy (TAO)
computed tomography (CT)
exophthalmos
title CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy
title_full CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy
title_fullStr CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy
title_full_unstemmed CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy
title_short CT features of exophthalmos in Chinese subjects with thyroid-associated ophthalmopathy
title_sort ct features of exophthalmos in chinese subjects with thyroid associated ophthalmopathy
topic thyroid-associated ophthalmopathy (TAO)
computed tomography (CT)
exophthalmos
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633750/
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