Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan
Objectives: This study investigated the prevalence of multidrug-resistant organisms (MDROs) in the residents and environments of long-term care facilities (LTCFs) in Taiwan. Methods: We prospectively investigated the distribution of MDROs in residents of six LTCFs and their environments from January...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-04-01
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| Series: | Journal of Microbiology, Immunology and Infection |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1684118217300166 |
| _version_ | 1818413583702163456 |
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| author | Chun-Ming Lee Chih-Cheng Lai Hsiu-Tzy Chiang Min-Chi Lu Ling-Fang Wang Tsai-Ling Tsai Mei-Yu Kang Yi-Ni Jan Yi-Ting Lo Wen-Chien Ko Shu-Hui Tseng Po-Ren Hsueh |
| author_facet | Chun-Ming Lee Chih-Cheng Lai Hsiu-Tzy Chiang Min-Chi Lu Ling-Fang Wang Tsai-Ling Tsai Mei-Yu Kang Yi-Ni Jan Yi-Ting Lo Wen-Chien Ko Shu-Hui Tseng Po-Ren Hsueh |
| author_sort | Chun-Ming Lee |
| collection | DOAJ |
| description | Objectives: This study investigated the prevalence of multidrug-resistant organisms (MDROs) in the residents and environments of long-term care facilities (LTCFs) in Taiwan.
Methods: We prospectively investigated the distribution of MDROs in residents of six LTCFs and their environments from January 2015 to December 2015 (intervention period). Active surveillance of colonization of MDROs was performed by culturing rectal and nasal swab samples every 3 months for the residents: 63, 79, and 73 in the first, second, and third surveillance investigations, respectively. If MDROs, including methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, carbapenem-resistant Pseudomonas aeruginosa, and MDR Acinetobacter baumannii were identified, then swab specimens from environmental sources were also collected and cultured. During the study period, several infection control measures were also implemented.
Results: The overall infection density decreased significantly from 2.69 per 1000 patient–days in the preintervention (January 2014 to December 2014) to 2.39 per 1000 patient–days during the intervention period (p < 0.001). A total of 154 samples from residents and environmental sources were positive for MDROs. Methicillin-resistant S. aureus (n = 83, 53.9%) was the predominant organism, followed by carbapenem-resistant Enterobacteriaceae (n = 35, 22.7%), MDR A. baumannii (n = 30, 19.5%), and carbapenem-resistant P. aeruginosa (n = 6, 3.9%). The rates of detection of MDROs were 27.9% (60/215) in nasal swabs, 15.8% (34/215) in rectal swabs, and 11.1% (60/542) in the environmental sources.
Conclusions: The distribution and persistence of MDROs varied among the different LTCFs and time periods. |
| first_indexed | 2024-12-14T11:05:31Z |
| format | Article |
| id | doaj.art-9b8067d044e445b98e41fc6501f0b831 |
| institution | Directory Open Access Journal |
| issn | 1684-1182 |
| language | English |
| last_indexed | 2024-12-14T11:05:31Z |
| publishDate | 2017-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Microbiology, Immunology and Infection |
| spelling | doaj.art-9b8067d044e445b98e41fc6501f0b8312022-12-21T23:04:32ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822017-04-0150213314410.1016/j.jmii.2016.12.001Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in TaiwanChun-Ming Lee0Chih-Cheng Lai1Hsiu-Tzy Chiang2Min-Chi Lu3Ling-Fang Wang4Tsai-Ling Tsai5Mei-Yu Kang6Yi-Ni Jan7Yi-Ting Lo8Wen-Chien Ko9Shu-Hui Tseng10Po-Ren Hsueh11Department of Internal Medicine, St. Joseph's Hospital, Yunlin County, TaiwanDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, TaiwanInfection Control Center, MacKay Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, Chung Shan Medical University, Taichung, TaiwanYongen Nursing Home, Taichung, TaiwanLukang Christian Nursing Home, Changhua, TaiwanChanghua Christian Hospital Erlin Nursing Home, Changhua, TaiwanThanksgiving Nursing Home, Taichung, TaiwanFeng-Fung Nursing Home, Taichung, TaiwanDepartment of Internal Medicine, National Cheng Kung University Hospital and Medical College, Tainan, TaiwanCenters for Disease Control, Ministry of Health and Welfare, Taipei, TaiwanDepartments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, TaiwanObjectives: This study investigated the prevalence of multidrug-resistant organisms (MDROs) in the residents and environments of long-term care facilities (LTCFs) in Taiwan. Methods: We prospectively investigated the distribution of MDROs in residents of six LTCFs and their environments from January 2015 to December 2015 (intervention period). Active surveillance of colonization of MDROs was performed by culturing rectal and nasal swab samples every 3 months for the residents: 63, 79, and 73 in the first, second, and third surveillance investigations, respectively. If MDROs, including methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, carbapenem-resistant Pseudomonas aeruginosa, and MDR Acinetobacter baumannii were identified, then swab specimens from environmental sources were also collected and cultured. During the study period, several infection control measures were also implemented. Results: The overall infection density decreased significantly from 2.69 per 1000 patient–days in the preintervention (January 2014 to December 2014) to 2.39 per 1000 patient–days during the intervention period (p < 0.001). A total of 154 samples from residents and environmental sources were positive for MDROs. Methicillin-resistant S. aureus (n = 83, 53.9%) was the predominant organism, followed by carbapenem-resistant Enterobacteriaceae (n = 35, 22.7%), MDR A. baumannii (n = 30, 19.5%), and carbapenem-resistant P. aeruginosa (n = 6, 3.9%). The rates of detection of MDROs were 27.9% (60/215) in nasal swabs, 15.8% (34/215) in rectal swabs, and 11.1% (60/542) in the environmental sources. Conclusions: The distribution and persistence of MDROs varied among the different LTCFs and time periods.http://www.sciencedirect.com/science/article/pii/S1684118217300166environmentinfection controllong-term care facilitymultidrug-resistant organismsresidents |
| spellingShingle | Chun-Ming Lee Chih-Cheng Lai Hsiu-Tzy Chiang Min-Chi Lu Ling-Fang Wang Tsai-Ling Tsai Mei-Yu Kang Yi-Ni Jan Yi-Ting Lo Wen-Chien Ko Shu-Hui Tseng Po-Ren Hsueh Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan Journal of Microbiology, Immunology and Infection environment infection control long-term care facility multidrug-resistant organisms residents |
| title | Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan |
| title_full | Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan |
| title_fullStr | Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan |
| title_full_unstemmed | Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan |
| title_short | Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan |
| title_sort | presence of multidrug resistant organisms in the residents and environments of long term care facilities in taiwan |
| topic | environment infection control long-term care facility multidrug-resistant organisms residents |
| url | http://www.sciencedirect.com/science/article/pii/S1684118217300166 |
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