Targeting HIF-1α by Natural and Synthetic Compounds: A Promising Approach for Anti-Cancer Therapeutics Development

Targeting HIF-1α by Natural and Synthetic Compounds: A Promising Approach for Anti-Cancer Therapeutics Development

Advancement in novel target detection using improved molecular cancer biology has opened up new avenues for promising anti-cancer drug development. In the past two decades, the mechanism of tumor hypoxia has become more understandable with the discovery of hypoxia-inducible factor-1α (HIF-1α). It is...

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Bibliographic Details
Main Authors: Rituparna Ghosh, Priya Samanta, Rupali Sarkar, Souradeep Biswas, Prosenjit Saha, Subhadip Hajra, Arijit Bhowmik
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
HIF-1α
hypoxia
metastasis
angiogenesis
cancer stem cells
natural compounds
Online Access:https://www.mdpi.com/1420-3049/27/16/5192

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