Low dose aerosol fitness at the innate phase of murine infection better predicts virulence amongst clinical strains of Mycobacterium tuberculosis.

BACKGROUND:Evaluation of a quick and easy model to determine the intrinsic ability of clinical strains to generate active TB has been set by assuming that this is linked to the fitness of Mycobacterium tuberculosis strain at the innate phase of the infection. Thus, the higher the bacillary load, the...

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Bibliographic Details
Main Authors: Neus Caceres, Isaac Llopis, Elena Marzo, Clara Prats, Cristina Vilaplana, Dario García de Viedma, Sofía Samper, Daniel Lopez, Pere-Joan Cardona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250398?pdf=render