Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases
PURPOSEWe aimed to determine the value of in vivo single voxel proton magnetic resonance spectroscopy (MRS) in characterizing breast lesions. MATERIALS AND METHODSBreast MRS was performed in 77 patients. Choline resonance peak at 3.2 parts per million (ppm) was defined positive when it was at least...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2013-05-01
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| Series: | Diagnostic and Interventional Radiology |
| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/single-voxel-in-vivo-proton-magnetic-resonance-spe/56689
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| _version_ | 1797691508776763392 |
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| author | Işıl Başara, Şebnem Örgüç, Teoman Coşkun |
| author_facet | Işıl Başara, Şebnem Örgüç, Teoman Coşkun |
| author_sort | Işıl Başara, |
| collection | DOAJ |
| description | PURPOSEWe aimed to determine the value of in vivo single voxel proton magnetic resonance spectroscopy (MRS) in characterizing breast lesions. MATERIALS AND METHODSBreast MRS was performed in 77 patients. Choline resonance peak at 3.2 parts per million (ppm) was defined positive when it was at least two times higher than baseline. MRS findings were compared with the final diagnosis of cases for two different values (3.23 and 3.28 ppm). RESULTSThirty-one malignant and 13 benign lesions had choline peaks. Sensitivity was 84%, specificity was 64%. Positive likelihood ratio (LHR) was 2.32, negative LHR was 0.25. Twenty-two malignant and 5 benign lesions had a peak at 3.23 ppm. Nine malignant and 8 benign lesions had a peak at 3.28 ppm. When 3.23 ppm was accepted as positive; sensitivity, specificity, and positive and negative LHRs were 79%, 82%, 4.4, and 0.26, respectively. CONCLUSIONMRS provides additional parameters on evaluation of breast lesions. However, MRS of breast has some false negative results, thus it is still insufficient in clinical diagnosis. |
| first_indexed | 2024-03-12T02:14:19Z |
| format | Article |
| id | doaj.art-9b85f7272dc0487cadbd5acdd5fd1168 |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-12T02:14:19Z |
| publishDate | 2013-05-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-9b85f7272dc0487cadbd5acdd5fd11682023-09-06T10:50:07ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122013-05-0119322122610.5152/dir.2012.00513049054Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 casesIşıl Başara,0Şebnem Örgüç,1Teoman Coşkun2 Department of Radiology, School of Medicine, Dokuz Eylul University, Izmir, Turkey Departments of Radiology, Celal Bayar University School of Medicine, Manisa, Turkey Departments of General Surgery, Celal Bayar University School of Medicine, Manisa, Turkey PURPOSEWe aimed to determine the value of in vivo single voxel proton magnetic resonance spectroscopy (MRS) in characterizing breast lesions. MATERIALS AND METHODSBreast MRS was performed in 77 patients. Choline resonance peak at 3.2 parts per million (ppm) was defined positive when it was at least two times higher than baseline. MRS findings were compared with the final diagnosis of cases for two different values (3.23 and 3.28 ppm). RESULTSThirty-one malignant and 13 benign lesions had choline peaks. Sensitivity was 84%, specificity was 64%. Positive likelihood ratio (LHR) was 2.32, negative LHR was 0.25. Twenty-two malignant and 5 benign lesions had a peak at 3.23 ppm. Nine malignant and 8 benign lesions had a peak at 3.28 ppm. When 3.23 ppm was accepted as positive; sensitivity, specificity, and positive and negative LHRs were 79%, 82%, 4.4, and 0.26, respectively. CONCLUSIONMRS provides additional parameters on evaluation of breast lesions. However, MRS of breast has some false negative results, thus it is still insufficient in clinical diagnosis. http://www.dirjournal.org/archives/archive-detail/article-preview/single-voxel-in-vivo-proton-magnetic-resonance-spe/56689 |
| spellingShingle | Işıl Başara, Şebnem Örgüç, Teoman Coşkun Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases Diagnostic and Interventional Radiology |
| title | Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases |
| title_full | Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases |
| title_fullStr | Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases |
| title_full_unstemmed | Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases |
| title_short | Single voxel in vivo proton magnetic resonance spectroscopy of breast lesions: experience in 77 cases |
| title_sort | single voxel in vivo proton magnetic resonance spectroscopy of breast lesions experience in 77 cases |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/single-voxel-in-vivo-proton-magnetic-resonance-spe/56689
|
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