Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation
Connexin 43 (Cx43) is the predominant connexin subtype expressed in osteocytes. Osteocytes, accounting for 90%–95% of total bone cells, function as orchestrators coordinating balanced activity between bone-resorbing osteoclasts and bone-forming osteoblasts. In this study, two newly developed osteocy...
Main Authors: | Rui Hua, Sumin Gu, Jean X. Jiang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-05-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2022.892229/full |
Similar Items
-
Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy
by: Manuel A. Riquelme, et al.
Published: (2024-07-01) -
Osteocytic Connexin43 Channels Regulate Bone–Muscle Crosstalk
by: Guobin Li, et al.
Published: (2021-01-01) -
Connexin 43 Channels in Osteocytes Regulate Bone Responses to Mechanical Unloading
by: Dezhi Zhao, et al.
Published: (2020-03-01) -
Inhibition by Commercial Aminoglycosides of Human Connexin Hemichannels Expressed in Bacteria
by: Mariana C. Fiori, et al.
Published: (2017-11-01) -
Astrocytic connexin 43‐hemichannels aggravate seizures by modulating blood‐brain barrier permeability in temporal lobe epilepsy mice
by: Honghong Song, et al.
Published: (2024-09-01)