Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient

Background: The aim of the present study was to investigate the effects of the left ventricular outflow gradient on tissue doppler imaging (TDI) values in patients with hypertrophic cardiomyopathy (HCM). Methods: This prospective observational study was conducted in a tertiary referral heart hospita...

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Main Authors: Rezvaneh Salehi, Azin Alizadehasl
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2010-02-01
Series:Journal of Cardiovascular and Thoracic Research
Subjects:
Online Access:http://journals.tbzmed.ac.ir/JCVTR/Manuscript/JCVTR-2-19.pdf
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author Rezvaneh Salehi
Azin Alizadehasl
author_facet Rezvaneh Salehi
Azin Alizadehasl
author_sort Rezvaneh Salehi
collection DOAJ
description Background: The aim of the present study was to investigate the effects of the left ventricular outflow gradient on tissue doppler imaging (TDI) values in patients with hypertrophic cardiomyopathy (HCM). Methods: This prospective observational study was conducted in a tertiary referral heart hospital (Tabriz, Iran) from March 2004 to March 2008. Fifty two patients (28 men and 24 women) with definite diagnoses of HCM were selected for the study. 2D, M-mode echocardiography and TDI were performed for all patients. In TDI, the velocities of myocardium was measured at lateral and septal corner of the mitral valve annulus in peak early diastolic (Ea), peak late diastolic (Aa) and peak systolic (Sa). Then, the TDI velocities were compared in patients with left ventricle outflow gradient less and more than 30 mmHg. Results: The mean age of the patients was 42.13 ± 12.22 years. All patients were in New York Heart Association functional class I or II. The mean EF was 55 ± 7%. It was found that TDI velocities are reduced in patients with HCM, compared to normal vaues and Ea in septal corners of the mitral annulus was reduced more in patients with left ventricle outflow gradient > 30 mmHg (5.3±1.6 vs 7.1±1.2, P=0.01). Conclusion: TDI findings specially peak early diastolic (Ea) mitral annular velocity are good parameters in HCM patients assessment.
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spelling doaj.art-9b869ce4f9e5473e861706ad62990a862022-12-21T18:30:47ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302010-02-01241922JCVTR_20130304105652Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow GradientRezvaneh Salehi0Azin Alizadehasl1Cardiovascular ResearchCenter, Tabriz University ofMedical Sciences, Tabriz, Iran.Cardiovascular ResearchCenter, Tabriz University ofMedical Sciences, Tabriz, Iran.Background: The aim of the present study was to investigate the effects of the left ventricular outflow gradient on tissue doppler imaging (TDI) values in patients with hypertrophic cardiomyopathy (HCM). Methods: This prospective observational study was conducted in a tertiary referral heart hospital (Tabriz, Iran) from March 2004 to March 2008. Fifty two patients (28 men and 24 women) with definite diagnoses of HCM were selected for the study. 2D, M-mode echocardiography and TDI were performed for all patients. In TDI, the velocities of myocardium was measured at lateral and septal corner of the mitral valve annulus in peak early diastolic (Ea), peak late diastolic (Aa) and peak systolic (Sa). Then, the TDI velocities were compared in patients with left ventricle outflow gradient less and more than 30 mmHg. Results: The mean age of the patients was 42.13 ± 12.22 years. All patients were in New York Heart Association functional class I or II. The mean EF was 55 ± 7%. It was found that TDI velocities are reduced in patients with HCM, compared to normal vaues and Ea in septal corners of the mitral annulus was reduced more in patients with left ventricle outflow gradient > 30 mmHg (5.3±1.6 vs 7.1±1.2, P=0.01). Conclusion: TDI findings specially peak early diastolic (Ea) mitral annular velocity are good parameters in HCM patients assessment.http://journals.tbzmed.ac.ir/JCVTR/Manuscript/JCVTR-2-19.pdfHypertrophic CardiomyopathyTissue Doppler ImagingLeft Ventricular Outflow Gradient
spellingShingle Rezvaneh Salehi
Azin Alizadehasl
Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient
Journal of Cardiovascular and Thoracic Research
Hypertrophic Cardiomyopathy
Tissue Doppler Imaging
Left Ventricular Outflow Gradient
title Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient
title_full Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient
title_fullStr Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient
title_full_unstemmed Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient
title_short Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy According to Left Ventricular Outflow Gradient
title_sort tissue doppler imaging values in hypertrophic cardiomyopathy according to left ventricular outflow gradient
topic Hypertrophic Cardiomyopathy
Tissue Doppler Imaging
Left Ventricular Outflow Gradient
url http://journals.tbzmed.ac.ir/JCVTR/Manuscript/JCVTR-2-19.pdf
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AT azinalizadehasl tissuedopplerimagingvaluesinhypertrophiccardiomyopathyaccordingtoleftventricularoutflowgradient