Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series
Enteroviruses are a common cause of neonatal infection. In particular, Coxsackie B viruses are often associated with severe, fatal disease. The antenatal diagnosis of Coxsackie B viral infections is uncommon. We present a unique case of Coxsackie B4 virus ventriculitis and myocarditis causing fetal...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2012-11-01
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| Series: | American Journal of Perinatology Reports |
| Subjects: | |
| Online Access: | https://www.thieme-connect.de/products/ejournals/html/10.1055/s-0031-1296027 |
| _version_ | 1811336958802132992 |
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| author | Jennifer C. Hunt Carol Schneider Savas Menticoglou Jayantha Herath Marc R. Del Bigio |
| author_facet | Jennifer C. Hunt Carol Schneider Savas Menticoglou Jayantha Herath Marc R. Del Bigio |
| author_sort | Jennifer C. Hunt |
| collection | DOAJ |
| description | Enteroviruses are a common cause of neonatal infection. In particular, Coxsackie B viruses are often associated with severe, fatal disease. The antenatal diagnosis of Coxsackie B viral infections is uncommon. We present a unique case of Coxsackie B4 virus ventriculitis and myocarditis causing fetal hydrops at 22 weeks gestation. Transmission was inferred by viral isolation from the amniotic fluid and by placental pathology. We also describe two additional cases of fatal neonatal Coxsackie B4 infection complicated by myocarditis and encephalitis with cerebral necrosis in a 4-day-old female and by myocarditis, spinal leptomeningitis, and hepatitis in a 4-day-old male. Transplacental acquisition of infection carries a poor prognosis. We propose that Coxsackie B virus should be considered in the investigation of nonimmune hydrops, particularly in the presence of cardiac dysfunction. |
| first_indexed | 2024-04-13T17:48:00Z |
| format | Article |
| id | doaj.art-9b87cbf23c6b4c2c9b07ba1157ef01b3 |
| institution | Directory Open Access Journal |
| issn | 2157-6998 2157-7005 |
| language | English |
| last_indexed | 2024-04-13T17:48:00Z |
| publishDate | 2012-11-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | American Journal of Perinatology Reports |
| spelling | doaj.art-9b87cbf23c6b4c2c9b07ba1157ef01b32022-12-22T02:36:53ZengThieme Medical Publishers, Inc.American Journal of Perinatology Reports2157-69982157-70052012-11-01020100100610.1055/s-0031-1296027Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case SeriesJennifer C. Hunt0Carol Schneider1Savas Menticoglou2Jayantha Herath3Marc R. Del Bigio4University of ManitobaUniversity of ManitobaUniversity of ManitobaUniversity of ManitobaUniversity of ManitobaEnteroviruses are a common cause of neonatal infection. In particular, Coxsackie B viruses are often associated with severe, fatal disease. The antenatal diagnosis of Coxsackie B viral infections is uncommon. We present a unique case of Coxsackie B4 virus ventriculitis and myocarditis causing fetal hydrops at 22 weeks gestation. Transmission was inferred by viral isolation from the amniotic fluid and by placental pathology. We also describe two additional cases of fatal neonatal Coxsackie B4 infection complicated by myocarditis and encephalitis with cerebral necrosis in a 4-day-old female and by myocarditis, spinal leptomeningitis, and hepatitis in a 4-day-old male. Transplacental acquisition of infection carries a poor prognosis. We propose that Coxsackie B virus should be considered in the investigation of nonimmune hydrops, particularly in the presence of cardiac dysfunction.https://www.thieme-connect.de/products/ejournals/html/10.1055/s-0031-1296027coxsackie B virushydropsmyocarditiscerebritisventriculitis |
| spellingShingle | Jennifer C. Hunt Carol Schneider Savas Menticoglou Jayantha Herath Marc R. Del Bigio Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series American Journal of Perinatology Reports coxsackie B virus hydrops myocarditis cerebritis ventriculitis |
| title | Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series |
| title_full | Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series |
| title_fullStr | Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series |
| title_full_unstemmed | Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series |
| title_short | Antenatal and Postnatal Diagnosis of Coxsackie B4 Infection: Case Series |
| title_sort | antenatal and postnatal diagnosis of coxsackie b4 infection case series |
| topic | coxsackie B virus hydrops myocarditis cerebritis ventriculitis |
| url | https://www.thieme-connect.de/products/ejournals/html/10.1055/s-0031-1296027 |
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