Innovative Three-Dimensional Microscopic Analysis of Uremic Growth Plate Discloses Alterations in the Process of Chondrocyte Hypertrophy: Effects of Growth Hormone Treatment

Innovative Three-Dimensional Microscopic Analysis of Uremic Growth Plate Discloses Alterations in the Process of Chondrocyte Hypertrophy: Effects of Growth Hormone Treatment

Chronic kidney disease (CKD) alters the morphology and function of the growth plate (GP) of long bones by disturbing chondrocyte maturation. GP chondrocytes were analyzed in growth-retarded young rats with CKD induced by adenine intake (AD), control rats fed ad libitum (C) or pair-fed with the AD gr...

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Bibliographic Details
Main Authors: Ángela Fernández-Iglesias, Rocío Fuente, Helena Gil-Peña, Laura Alonso-Durán, María García-Bengoa, Fernando Santos, José Manuel López
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
chronic kidney disease
CKD
uremia
chondrocyte
hypertrophy
GH
Online Access:https://www.mdpi.com/1422-0067/21/12/4519

Internet

https://www.mdpi.com/1422-0067/21/12/4519

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