Celastrol induces premature ovarian insufficiency by inducing apoptosis in granulosa cells

Celastrol induces premature ovarian insufficiency by inducing apoptosis in granulosa cells

Celastrol, a natural compound purified from the Chinese herb Tripterygium wilfordii Hook. f., has excellent pharmacological activity for the treatment of various diseases. Assessing the safety of its use is essential for its development into a clinical medicine. However, research assessing its toxic...

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Bibliographic Details
Main Authors:	Fan Wen, Dandan Liu, Mingming Wang, Shujie Zhang, Wenhua Kuang, Lixia Yuan, Jigang Wang, Gang Liu
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Celastrol Premature ovarian insufficiency Granulosa cell Apoptosis Activity-based protein profiling
Online Access:	http://www.sciencedirect.com/science/article/pii/S075333222301613X

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