Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer
Breast re-irradiation (reRT) after breast-conserving surgery (BCS) using external beam radiation is an increasingly used salvage approach for women presenting with recurrent or new primary breast cancer. However, radiation technique, dose and fractionation as well as eligibility criteria differ betw...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/30/1/88 |
| _version_ | 1827626963023429632 |
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| author | Camille Hardy Abeloos Juhi M. Purswani Paulina Galavis Allison McCarthy Christine Hitchen J. Isabelle Choi Naamit K. Gerber |
| author_facet | Camille Hardy Abeloos Juhi M. Purswani Paulina Galavis Allison McCarthy Christine Hitchen J. Isabelle Choi Naamit K. Gerber |
| author_sort | Camille Hardy Abeloos |
| collection | DOAJ |
| description | Breast re-irradiation (reRT) after breast-conserving surgery (BCS) using external beam radiation is an increasingly used salvage approach for women presenting with recurrent or new primary breast cancer. However, radiation technique, dose and fractionation as well as eligibility criteria differ between studies. There is also limited data on efficacy and safety of external beam hypofractionation and accelerated partial-breast irradiation (APBI) regimens. This paper reviews existing retrospective and prospective data for breast reRT after BCS, APBI reRT outcomes and delivery at our institution and the need for a randomized controlled trial using shorter courses of radiation to better define patient selection for different reRT fractionation regimens. |
| first_indexed | 2024-03-09T13:04:57Z |
| format | Article |
| id | doaj.art-9b8cb4455e7f4cf9867170e18b87c6b5 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-09T13:04:57Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-9b8cb4455e7f4cf9867170e18b87c6b52023-11-30T21:50:06ZengMDPI AGCurrent Oncology1198-00521718-77292023-01-013011151116310.3390/curroncol30010088Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast CancerCamille Hardy Abeloos0Juhi M. Purswani1Paulina Galavis2Allison McCarthy3Christine Hitchen4J. Isabelle Choi5Naamit K. Gerber6Department of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USADepartment of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USADepartment of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USADepartment of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USADepartment of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USADepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USADepartment of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USABreast re-irradiation (reRT) after breast-conserving surgery (BCS) using external beam radiation is an increasingly used salvage approach for women presenting with recurrent or new primary breast cancer. However, radiation technique, dose and fractionation as well as eligibility criteria differ between studies. There is also limited data on efficacy and safety of external beam hypofractionation and accelerated partial-breast irradiation (APBI) regimens. This paper reviews existing retrospective and prospective data for breast reRT after BCS, APBI reRT outcomes and delivery at our institution and the need for a randomized controlled trial using shorter courses of radiation to better define patient selection for different reRT fractionation regimens.https://www.mdpi.com/1718-7729/30/1/88breast re-irradiationtoxicityoutcomeeligibility |
| spellingShingle | Camille Hardy Abeloos Juhi M. Purswani Paulina Galavis Allison McCarthy Christine Hitchen J. Isabelle Choi Naamit K. Gerber Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer Current Oncology breast re-irradiation toxicity outcome eligibility |
| title | Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer |
| title_full | Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer |
| title_fullStr | Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer |
| title_full_unstemmed | Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer |
| title_short | Different Re-Irradiation Techniques after Breast-Conserving Surgery for Recurrent or New Primary Breast Cancer |
| title_sort | different re irradiation techniques after breast conserving surgery for recurrent or new primary breast cancer |
| topic | breast re-irradiation toxicity outcome eligibility |
| url | https://www.mdpi.com/1718-7729/30/1/88 |
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