Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice

Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice

Ischemic stroke (IS) is a vascular disease group concomitant with high morbidity and mortality. Berberine is a bioactive substance and it has been known to improve stroke, but its mechanism is yet to be proven. Mice were fed with BBR for 14 days. Then, the mice were made into MCAO/R models. Neurolog...

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Bibliographic Details
Main Authors: Huijie Duan, Junya Hu, Yang Deng, Junqing Zou, Wangli Ding, Qiang Peng, Rui Duan, Jianguo Sun, Junrong Zhu
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Nutrients
Subjects:
stroke
gut microbiota
butyric acid
microglia
astrocytes
NLRP3
Online Access:https://www.mdpi.com/2072-6643/16/1/9

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