Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis

Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis

Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase-13 (MMP-13) is the primary MMP involved in cartilage degradation through its particular ability to cleave type II col...

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Bibliographic Details
Main Authors: Qichan Hu, Melanie Ecker
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
osteoarthritis
cartilage
type II collagen
matrix metalloproteinases
MMP-13
regulation
Online Access:https://www.mdpi.com/1422-0067/22/4/1742

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