Can natural proteins designed with 'inverted' peptide sequences adopt native-like protein folds?
We have carried out a systematic computational analysis on a representative dataset of proteins of known three-dimensional structure, in order to evaluate whether it would possible to 'swap' certain short peptide sequences in naturally occurring proteins with their corresponding 'inve...
Main Authors: | Settu Sridhar, Kunchur Guruprasad |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4161436?pdf=render |
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