Acrogeria: A rare congenital aging syndrome
Acrogeria is a rare, nonhereditary genetic syndrome that presents with nonprogressive atrophy of the skin of the distal extremities, giving it an aged appearance. The patients have characteristic facies with pinched faces, an “owl-eyed” appearance, and a beaked nose. We report a 14-year-old female p...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Paediatric Dermatology |
| Subjects: | |
| Online Access: | http://www.ijpd.in/article.asp?issn=2319-7250;year=2023;volume=24;issue=4;spage=307;epage=310;aulast=Thirumalaiswamy |
| _version_ | 1797300030171774976 |
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| author | Aparna Thirumalaiswamy Vidya D Kharkar Anmol Bhargava |
| author_facet | Aparna Thirumalaiswamy Vidya D Kharkar Anmol Bhargava |
| author_sort | Aparna Thirumalaiswamy |
| collection | DOAJ |
| description | Acrogeria is a rare, nonhereditary genetic syndrome that presents with nonprogressive atrophy of the skin of the distal extremities, giving it an aged appearance. The patients have characteristic facies with pinched faces, an “owl-eyed” appearance, and a beaked nose. We report a 14-year-old female patient of acrogeria who presented with typical clinical findings and dermoscopic features. Acrogeria, with onset usually at birth or thereafter, is often sporadic with potential genetic underpinnings. Uncommon features encompass skeletal and soft-tissue anomalies. The prognosis is generally favorable for these patients due to the lack of systemic involvement. To the best of our knowledge, dermoscopic features of acrogeria have not been described previously. We report this case owing to its rarity and to describe the dermoscopic features seen in this rare syndrome. |
| first_indexed | 2024-03-07T23:00:18Z |
| format | Article |
| id | doaj.art-9b978bb352f0463ba1fe139e4985582f |
| institution | Directory Open Access Journal |
| issn | 2319-7250 |
| language | English |
| last_indexed | 2024-03-07T23:00:18Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Paediatric Dermatology |
| spelling | doaj.art-9b978bb352f0463ba1fe139e4985582f2024-02-22T14:56:35ZengWolters Kluwer Medknow PublicationsIndian Journal of Paediatric Dermatology2319-72502023-01-0124430731010.4103/ijpd.ijpd_10_23Acrogeria: A rare congenital aging syndromeAparna ThirumalaiswamyVidya D KharkarAnmol BhargavaAcrogeria is a rare, nonhereditary genetic syndrome that presents with nonprogressive atrophy of the skin of the distal extremities, giving it an aged appearance. The patients have characteristic facies with pinched faces, an “owl-eyed” appearance, and a beaked nose. We report a 14-year-old female patient of acrogeria who presented with typical clinical findings and dermoscopic features. Acrogeria, with onset usually at birth or thereafter, is often sporadic with potential genetic underpinnings. Uncommon features encompass skeletal and soft-tissue anomalies. The prognosis is generally favorable for these patients due to the lack of systemic involvement. To the best of our knowledge, dermoscopic features of acrogeria have not been described previously. We report this case owing to its rarity and to describe the dermoscopic features seen in this rare syndrome.http://www.ijpd.in/article.asp?issn=2319-7250;year=2023;volume=24;issue=4;spage=307;epage=310;aulast=Thirumalaiswamyacroosteolysiscongenitaldermoscopymicrognathiapoikilodermatelangiectasia |
| spellingShingle | Aparna Thirumalaiswamy Vidya D Kharkar Anmol Bhargava Acrogeria: A rare congenital aging syndrome Indian Journal of Paediatric Dermatology acroosteolysis congenital dermoscopy micrognathia poikiloderma telangiectasia |
| title | Acrogeria: A rare congenital aging syndrome |
| title_full | Acrogeria: A rare congenital aging syndrome |
| title_fullStr | Acrogeria: A rare congenital aging syndrome |
| title_full_unstemmed | Acrogeria: A rare congenital aging syndrome |
| title_short | Acrogeria: A rare congenital aging syndrome |
| title_sort | acrogeria a rare congenital aging syndrome |
| topic | acroosteolysis congenital dermoscopy micrognathia poikiloderma telangiectasia |
| url | http://www.ijpd.in/article.asp?issn=2319-7250;year=2023;volume=24;issue=4;spage=307;epage=310;aulast=Thirumalaiswamy |
| work_keys_str_mv | AT aparnathirumalaiswamy acrogeriaararecongenitalagingsyndrome AT vidyadkharkar acrogeriaararecongenitalagingsyndrome AT anmolbhargava acrogeriaararecongenitalagingsyndrome |