Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study
AimTo investigate the incidence of frozen shoulder and risk factors for the onset of frozen shoulder in middle-aged and elderly subjects within 1 year of discharge from a hospitalization that involved intravenous infusion in Zhangjiagang Second People's Hospital.MethodsA total of 1,900 subjects...
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Frontiers Media S.A.
2022-06-01
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Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.911532/full |
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author | Wenping Cao Jiangnan Chen Jianfeng Pu Yunwu Fan Ye Cao |
author_facet | Wenping Cao Jiangnan Chen Jianfeng Pu Yunwu Fan Ye Cao |
author_sort | Wenping Cao |
collection | DOAJ |
description | AimTo investigate the incidence of frozen shoulder and risk factors for the onset of frozen shoulder in middle-aged and elderly subjects within 1 year of discharge from a hospitalization that involved intravenous infusion in Zhangjiagang Second People's Hospital.MethodsA total of 1,900 subjects who were discharged from a hospitalization that involved intravenous infusion in the hospital between May 2020 and September 2020 met the inclusion criteria for this study: 950 subjects had a mean daily duration of intravenous infusion ≤ 2 h (low exposure) and 950 subjects had a mean daily duration of intravenous infusion ≥3 h (high exposure). Subjects were followed up by telephone at 6 months ± 1 week and 12 months ± 1 week after discharge the incidence of frozen shoulder.ResultsThe cumulative incidence rate of frozen shoulder within 1 year of discharge was 5.2%. Multivariate logistic regression analysis revealed the risk of frozen shoulder was higher in subjects with a mean daily duration of intravenous infusion ≥3 h compared to ≤ 2 h (OR = 3.082, 95% CI 1.919–4.949, P < 0.001); subjects hospitalized for 11–30 days had a higher risk of frozen shoulder compared to those hospitalized for 10 days or less (OR = 6.836, 95%CI 4.363–10.709, P < 0.001); subjects who were overweight/ obese (BMI ≥ 25 kg/m2) had a higher risk of frozen shoulder compared to those of normal weight (BMI 18.5–24.9 kg/m2) (OR = 2.166, 95%CI 1.376–3.410, P = 0.001); subjects in the 56–70-year-old age group had a higher risk of developing frozen shoulder compared to those in the 40–55-year-old age group (OR = 1.977, 95%CI 1.154–3.387, P = 0.013); diabetes increased the risk of frozen shoulder (OR = 3.009, 95%CI 1.826–4.959, P < 0.001). The 71–85 years old age group and hypertension were statistically significant in univariate analysis but not in multivariate analysis (P > 0.05).ConclusionCompared with middle-aged and elderly in the general population, middle-aged and elderly subjects who received intravenous infusion during a hospitalization had a higher cumulative incidence rate of frozen shoulder within 1 year after discharge. Independent risk factors for the onset of frozen shoulder included mean daily duration of intravenous infusion ≥3 h, length of hospital stay 11–30 days, BMI ≥ 25 kg/m2, age 56–70 years, and diabetes. |
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spelling | doaj.art-9b97a048d47746afbfb8fba2c2fc06132022-12-22T00:18:46ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-06-01910.3389/fmed.2022.911532911532Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort StudyWenping Cao0Jiangnan Chen1Jianfeng Pu2Yunwu Fan3Ye Cao4Department of Acupuncture, Zhangjiagang Second People's Hospital, Zhangjiagang City, ChinaDepartment of Acupuncture, Zhangjiagang Second People's Hospital, Zhangjiagang City, ChinaDepartment of Acupuncture, Zhangjiagang Second People's Hospital, Zhangjiagang City, ChinaDepartment of Pain Medicine, Zhangjiagang Second People's Hospital, Zhangjiagang City, ChinaDepartment of Pain Medicine, Zhangjiagang Second People's Hospital, Zhangjiagang City, ChinaAimTo investigate the incidence of frozen shoulder and risk factors for the onset of frozen shoulder in middle-aged and elderly subjects within 1 year of discharge from a hospitalization that involved intravenous infusion in Zhangjiagang Second People's Hospital.MethodsA total of 1,900 subjects who were discharged from a hospitalization that involved intravenous infusion in the hospital between May 2020 and September 2020 met the inclusion criteria for this study: 950 subjects had a mean daily duration of intravenous infusion ≤ 2 h (low exposure) and 950 subjects had a mean daily duration of intravenous infusion ≥3 h (high exposure). Subjects were followed up by telephone at 6 months ± 1 week and 12 months ± 1 week after discharge the incidence of frozen shoulder.ResultsThe cumulative incidence rate of frozen shoulder within 1 year of discharge was 5.2%. Multivariate logistic regression analysis revealed the risk of frozen shoulder was higher in subjects with a mean daily duration of intravenous infusion ≥3 h compared to ≤ 2 h (OR = 3.082, 95% CI 1.919–4.949, P < 0.001); subjects hospitalized for 11–30 days had a higher risk of frozen shoulder compared to those hospitalized for 10 days or less (OR = 6.836, 95%CI 4.363–10.709, P < 0.001); subjects who were overweight/ obese (BMI ≥ 25 kg/m2) had a higher risk of frozen shoulder compared to those of normal weight (BMI 18.5–24.9 kg/m2) (OR = 2.166, 95%CI 1.376–3.410, P = 0.001); subjects in the 56–70-year-old age group had a higher risk of developing frozen shoulder compared to those in the 40–55-year-old age group (OR = 1.977, 95%CI 1.154–3.387, P = 0.013); diabetes increased the risk of frozen shoulder (OR = 3.009, 95%CI 1.826–4.959, P < 0.001). The 71–85 years old age group and hypertension were statistically significant in univariate analysis but not in multivariate analysis (P > 0.05).ConclusionCompared with middle-aged and elderly in the general population, middle-aged and elderly subjects who received intravenous infusion during a hospitalization had a higher cumulative incidence rate of frozen shoulder within 1 year after discharge. Independent risk factors for the onset of frozen shoulder included mean daily duration of intravenous infusion ≥3 h, length of hospital stay 11–30 days, BMI ≥ 25 kg/m2, age 56–70 years, and diabetes.https://www.frontiersin.org/articles/10.3389/fmed.2022.911532/fullfrozen shoulderhospitalized patientsintravenous fluidrisk factorscohort study |
spellingShingle | Wenping Cao Jiangnan Chen Jianfeng Pu Yunwu Fan Ye Cao Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study Frontiers in Medicine frozen shoulder hospitalized patients intravenous fluid risk factors cohort study |
title | Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study |
title_full | Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study |
title_fullStr | Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study |
title_full_unstemmed | Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study |
title_short | Risk Factors for the Onset of Frozen Shoulder in Middle-Aged and Elderly Subjects Within 1 Year of Discharge From a Hospitalization That Involved Intravenous Infusion: A Prospective Cohort Study |
title_sort | risk factors for the onset of frozen shoulder in middle aged and elderly subjects within 1 year of discharge from a hospitalization that involved intravenous infusion a prospective cohort study |
topic | frozen shoulder hospitalized patients intravenous fluid risk factors cohort study |
url | https://www.frontiersin.org/articles/10.3389/fmed.2022.911532/full |
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