Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty<sup>®</sup>; BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/11/6/576 |
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| author | Elissavet Kontou Kyriaki Ranellou Dimitrios Zoulas Anastasia Bletsa Eirini Rompola Evangelia-Theophano Piperaki Nikolaos Athanasiou Kleio Ampelakiotou Maria Pratikaki Christina Stergiopoulou Athina Argyropoulou Androula Alevra Aggeliki Megalou Alexandra Tsirogianni |
| author_facet | Elissavet Kontou Kyriaki Ranellou Dimitrios Zoulas Anastasia Bletsa Eirini Rompola Evangelia-Theophano Piperaki Nikolaos Athanasiou Kleio Ampelakiotou Maria Pratikaki Christina Stergiopoulou Athina Argyropoulou Androula Alevra Aggeliki Megalou Alexandra Tsirogianni |
| author_sort | Elissavet Kontou |
| collection | DOAJ |
| description | We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty<sup>®</sup>; BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personnel working in COVID-19 clinics. Notably, individuals with a prior COVID-19 infection mounted a significantly higher antibody titer following the first dose than the rest of the population; the same was true for those working in COVID-19 clinics, even without history of previous infection. |
| first_indexed | 2024-03-10T10:15:45Z |
| format | Article |
| id | doaj.art-9b990b44f19b4443a00821af6349063c |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T10:15:45Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-9b990b44f19b4443a00821af6349063c2023-11-22T00:49:53ZengMDPI AGJournal of Personalized Medicine2075-44262021-06-0111657610.3390/jpm11060576Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, GreeceElissavet Kontou0Kyriaki Ranellou1Dimitrios Zoulas2Anastasia Bletsa3Eirini Rompola4Evangelia-Theophano Piperaki5Nikolaos Athanasiou6Kleio Ampelakiotou7Maria Pratikaki8Christina Stergiopoulou9Athina Argyropoulou10Androula Alevra11Aggeliki Megalou12Alexandra Tsirogianni13Immunology-Histocompatibility Department, “Evangelismos” General Hospital, 10676 Athens, GreeceMicrobiology Department, “Evangelismos” General Hospital, 10676 Athens, GreeceBlood Bank Department, “Evangelismos” General Hospital, 10676 Athens, GreeceImmunology-Histocompatibility Department, “Evangelismos” General Hospital, 10676 Athens, GreeceClinical Biochemistry Department, “Evangelismos” General Hospital, 10676 Athens, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceSt ICU, “Evangelismos” General Hospital, 10676 Athens, GreeceImmunology-Histocompatibility Department, “Evangelismos” General Hospital, 10676 Athens, GreeceClinical Biochemistry Department, “Evangelismos” General Hospital, 10676 Athens, GreeceBlood Bank Department, “Evangelismos” General Hospital, 10676 Athens, GreeceMicrobiology Department, “Evangelismos” General Hospital, 10676 Athens, GreeceClinical Biochemistry Department, “Evangelismos” General Hospital, 10676 Athens, GreeceBlood Bank Department, “Evangelismos” General Hospital, 10676 Athens, GreeceImmunology-Histocompatibility Department, “Evangelismos” General Hospital, 10676 Athens, GreeceWe analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty<sup>®</sup>; BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personnel working in COVID-19 clinics. Notably, individuals with a prior COVID-19 infection mounted a significantly higher antibody titer following the first dose than the rest of the population; the same was true for those working in COVID-19 clinics, even without history of previous infection.https://www.mdpi.com/2075-4426/11/6/576SARS CoV-2mRNA vaccineantibody responsehealthcare workers |
| spellingShingle | Elissavet Kontou Kyriaki Ranellou Dimitrios Zoulas Anastasia Bletsa Eirini Rompola Evangelia-Theophano Piperaki Nikolaos Athanasiou Kleio Ampelakiotou Maria Pratikaki Christina Stergiopoulou Athina Argyropoulou Androula Alevra Aggeliki Megalou Alexandra Tsirogianni Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece Journal of Personalized Medicine SARS CoV-2 mRNA vaccine antibody response healthcare workers |
| title | Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece |
| title_full | Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece |
| title_fullStr | Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece |
| title_full_unstemmed | Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece |
| title_short | Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece |
| title_sort | antibody response following a two dose mrna vaccination regimen in health care workers of a tertiary hospital in athens greece |
| topic | SARS CoV-2 mRNA vaccine antibody response healthcare workers |
| url | https://www.mdpi.com/2075-4426/11/6/576 |
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