Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study
Pressure ulcers are associated with multiple comorbidities and annually affect approximately 3 million Americans, directly accounting for approximately 60,000 deaths per year. Because patients with end-stage renal disease (ESRD) are known to present with unique factors which impair wound healing, pr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/8/1713 |
| _version_ | 1797584117387231232 |
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| author | Gabriela A. Duchesne Jennifer L. Waller Stephanie L. Baer Lufei Young Wendy B. Bollag |
| author_facet | Gabriela A. Duchesne Jennifer L. Waller Stephanie L. Baer Lufei Young Wendy B. Bollag |
| author_sort | Gabriela A. Duchesne |
| collection | DOAJ |
| description | Pressure ulcers are associated with multiple comorbidities and annually affect approximately 3 million Americans, directly accounting for approximately 60,000 deaths per year. Because patients with end-stage renal disease (ESRD) are known to present with unique factors which impair wound healing, pressure ulcers diagnosed in ESRD patients might independently increase the risk of mortality. To investigate the association between pressure ulcer diagnosis and mortality risk in the ESRD population, a retrospective analysis of the United States Renal Data System (USRDS) database was performed. The records of 1,526,366 dialysis patients who began therapy between 1 January 2005 and 31 December 2018 were included. Our analysis showed that the diagnosis of pressure ulcers in this population was independently associated with mortality even after controlling for confounding factors (<i>p</i> < 0.001). A Kaplan–Meier survival analysis demonstrated reduced survival in patients with a pressure ulcer diagnosis compared to those without a pressure ulcer diagnosis. These results establish pressure ulcers as a significant independent risk factor for mortality, as well as suggesting several comorbidities as potential risk factors for pressure ulcers in the ESRD population. |
| first_indexed | 2024-03-10T23:47:45Z |
| format | Article |
| id | doaj.art-9b9ac44a27ac466eb5bbe2d9f0bc027a |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T23:47:45Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-9b9ac44a27ac466eb5bbe2d9f0bc027a2023-11-19T01:54:32ZengMDPI AGLife2075-17292023-08-01138171310.3390/life13081713Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective StudyGabriela A. Duchesne0Jennifer L. Waller1Stephanie L. Baer2Lufei Young3Wendy B. Bollag4Department of Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USADepartment of Population Health Sciences, Medical College of Georgia at Augusta University, Augusta, GA 30912, USADepartment of Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USADepartment of Physiological and Technological Nursing, Augusta University, Augusta, GA 30912, USADepartment of Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USAPressure ulcers are associated with multiple comorbidities and annually affect approximately 3 million Americans, directly accounting for approximately 60,000 deaths per year. Because patients with end-stage renal disease (ESRD) are known to present with unique factors which impair wound healing, pressure ulcers diagnosed in ESRD patients might independently increase the risk of mortality. To investigate the association between pressure ulcer diagnosis and mortality risk in the ESRD population, a retrospective analysis of the United States Renal Data System (USRDS) database was performed. The records of 1,526,366 dialysis patients who began therapy between 1 January 2005 and 31 December 2018 were included. Our analysis showed that the diagnosis of pressure ulcers in this population was independently associated with mortality even after controlling for confounding factors (<i>p</i> < 0.001). A Kaplan–Meier survival analysis demonstrated reduced survival in patients with a pressure ulcer diagnosis compared to those without a pressure ulcer diagnosis. These results establish pressure ulcers as a significant independent risk factor for mortality, as well as suggesting several comorbidities as potential risk factors for pressure ulcers in the ESRD population.https://www.mdpi.com/2075-1729/13/8/1713pressure ulcerdialysismortalitychronic woundsend-stage renal disease |
| spellingShingle | Gabriela A. Duchesne Jennifer L. Waller Stephanie L. Baer Lufei Young Wendy B. Bollag Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study Life pressure ulcer dialysis mortality chronic wounds end-stage renal disease |
| title | Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study |
| title_full | Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study |
| title_fullStr | Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study |
| title_full_unstemmed | Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study |
| title_short | Pressure Ulcer Diagnosis Is Associated with Increased Mortality in Patients with End-Stage Renal Disease: A Retrospective Study |
| title_sort | pressure ulcer diagnosis is associated with increased mortality in patients with end stage renal disease a retrospective study |
| topic | pressure ulcer dialysis mortality chronic wounds end-stage renal disease |
| url | https://www.mdpi.com/2075-1729/13/8/1713 |
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