Case report: Methemoglobinemia caused by nitrobenzene poisoning
Nitrobenzene poisoning is uncommon, with most cases occurring in the dye, paint, and other chemical industries. Nitrobenzene enters the body mainly through the skin, respiratory tract, and oral cavity. Nitrobenzene poisoning symptoms include hypermethemoglobinemia, hemolytic anemia, liver and kidney...
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| Format: | Article |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1096644/full |
| _version_ | 1828011244534104064 |
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| author | Liwen Zhao Liwen Zhao Tianzi Jian Tianzi Jian Longke Shi Longke Shi Yaqian Li Zixin Wen Zixin Wen Zixin Wen Zixin Wen Lanlan Guo Lanlan Guo Qilu Li Xiangdong Jian Xiangdong Jian |
| author_facet | Liwen Zhao Liwen Zhao Tianzi Jian Tianzi Jian Longke Shi Longke Shi Yaqian Li Zixin Wen Zixin Wen Zixin Wen Zixin Wen Lanlan Guo Lanlan Guo Qilu Li Xiangdong Jian Xiangdong Jian |
| author_sort | Liwen Zhao |
| collection | DOAJ |
| description | Nitrobenzene poisoning is uncommon, with most cases occurring in the dye, paint, and other chemical industries. Nitrobenzene enters the body mainly through the skin, respiratory tract, and oral cavity. Nitrobenzene poisoning symptoms include hypermethemoglobinemia, hemolytic anemia, liver and kidney dysfunction, cardiogenic pulmonary edema, and toxic encephalopathy, which endanger people’s lives. Therefore, we present a case of nitrobenzene poisoning caused by skin absorption, focusing on its clinical characteristics and treatment outcomes. A 58 years-old man presented to our department with confusion and cyanosis. He has a history of hypertension and cerebral infarction. The patient was diagnosed with moderate occupational acute benzene poisoning with nitro compounds. Symptomatic support, methylene blue, and other antioxidant treatments were commenced after diagnosis. After treatment, the patient’s condition gradually improved, and he was discharged. |
| first_indexed | 2024-04-10T09:12:20Z |
| format | Article |
| id | doaj.art-9b9ac9c8e0354af286e61a6d9a3dca4f |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T09:12:20Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-9b9ac9c8e0354af286e61a6d9a3dca4f2023-02-21T04:42:20ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-02-011010.3389/fmed.2023.10966441096644Case report: Methemoglobinemia caused by nitrobenzene poisoningLiwen Zhao0Liwen Zhao1Tianzi Jian2Tianzi Jian3Longke Shi4Longke Shi5Yaqian Li6Zixin Wen7Zixin Wen8Zixin Wen9Zixin Wen10Lanlan Guo11Lanlan Guo12Qilu Li13Xiangdong Jian14Xiangdong Jian15Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaSchool of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong ChinaNursing Theory and Practice Innovation Research Center, Shandong University, Jinan, Shandong, ChinaDepartment of Nursing, Qilu Hospital of Shandong University, Jinan, Shandong ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaThe Hospital of Shandong University, Jinan, Shandong, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaDepartment of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ChinaNitrobenzene poisoning is uncommon, with most cases occurring in the dye, paint, and other chemical industries. Nitrobenzene enters the body mainly through the skin, respiratory tract, and oral cavity. Nitrobenzene poisoning symptoms include hypermethemoglobinemia, hemolytic anemia, liver and kidney dysfunction, cardiogenic pulmonary edema, and toxic encephalopathy, which endanger people’s lives. Therefore, we present a case of nitrobenzene poisoning caused by skin absorption, focusing on its clinical characteristics and treatment outcomes. A 58 years-old man presented to our department with confusion and cyanosis. He has a history of hypertension and cerebral infarction. The patient was diagnosed with moderate occupational acute benzene poisoning with nitro compounds. Symptomatic support, methylene blue, and other antioxidant treatments were commenced after diagnosis. After treatment, the patient’s condition gradually improved, and he was discharged.https://www.frontiersin.org/articles/10.3389/fmed.2023.1096644/fullnitrobenzenemethemoglobinemiahemolytic anemiatoxic encephalopathycyanosis |
| spellingShingle | Liwen Zhao Liwen Zhao Tianzi Jian Tianzi Jian Longke Shi Longke Shi Yaqian Li Zixin Wen Zixin Wen Zixin Wen Zixin Wen Lanlan Guo Lanlan Guo Qilu Li Xiangdong Jian Xiangdong Jian Case report: Methemoglobinemia caused by nitrobenzene poisoning Frontiers in Medicine nitrobenzene methemoglobinemia hemolytic anemia toxic encephalopathy cyanosis |
| title | Case report: Methemoglobinemia caused by nitrobenzene poisoning |
| title_full | Case report: Methemoglobinemia caused by nitrobenzene poisoning |
| title_fullStr | Case report: Methemoglobinemia caused by nitrobenzene poisoning |
| title_full_unstemmed | Case report: Methemoglobinemia caused by nitrobenzene poisoning |
| title_short | Case report: Methemoglobinemia caused by nitrobenzene poisoning |
| title_sort | case report methemoglobinemia caused by nitrobenzene poisoning |
| topic | nitrobenzene methemoglobinemia hemolytic anemia toxic encephalopathy cyanosis |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1096644/full |
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