Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy

Objective. To study the functional outcomes of rheumatoid arthritis (RA) 1, 3, 5, and 8 years after use of various procedures of anti-inflammatory therapy. Subjects and methods. One hundred patients with valid RA were examined. The patients were divided into 3 groups: 1) 38 patients received basic a...

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Huvudupphovsmän: Natalya Vladimirovna Chichasova, S A Vladimirov, G R Imametdinova, E V Igolkina, E L Nasonov
Materialtyp: Artikel
Språk:Russian
Publicerad: IMA PRESS LLC 2010-04-01
Serie:Научно-практическая ревматология
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Länkar:https://rsp.mediar-press.net/rsp/article/view/1252
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author Natalya Vladimirovna Chichasova
S A Vladimirov
G R Imametdinova
E V Igolkina
E L Nasonov
author_facet Natalya Vladimirovna Chichasova
S A Vladimirov
G R Imametdinova
E V Igolkina
E L Nasonov
author_sort Natalya Vladimirovna Chichasova
collection DOAJ
description Objective. To study the functional outcomes of rheumatoid arthritis (RA) 1, 3, 5, and 8 years after use of various procedures of anti-inflammatory therapy. Subjects and methods. One hundred patients with valid RA were examined. The patients were divided into 3 groups: 1) 38 patients received basic anti-inflammatory drugs (BAIDs) only; 2) 37 patients took BAIDs in combination with glucocorticoids (GCs); 3) 25 patients had synchronous programmed intensive therapy. Results. The early use of therapy with BAIDs without GCs in controlled therapy allows functional outcome improvement in patients in RA to greater extent. No therapy control leads to functional outcome worsening in RA. During a long follow-up, there is a reduction in the correlation of the Health Assessment Questionnaire (HAQ) scores with the parameters reflecting disease activity and an increase in the correlation of the HAQ with those reflecting the progression of RA. The development of the structural and anatomic changes in hand periarticular tissues with the formation of irreversible deformities does not correlate with the HAQ score in patients with RA.
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spelling doaj.art-9b9afcc853064b8392ec117a1934c0082025-03-02T13:23:34ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922010-04-01482303610.14412/1995-4484-2010-14131192Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapyNatalya Vladimirovna ChichasovaS A VladimirovG R ImametdinovaE V IgolkinaE L NasonovObjective. To study the functional outcomes of rheumatoid arthritis (RA) 1, 3, 5, and 8 years after use of various procedures of anti-inflammatory therapy. Subjects and methods. One hundred patients with valid RA were examined. The patients were divided into 3 groups: 1) 38 patients received basic anti-inflammatory drugs (BAIDs) only; 2) 37 patients took BAIDs in combination with glucocorticoids (GCs); 3) 25 patients had synchronous programmed intensive therapy. Results. The early use of therapy with BAIDs without GCs in controlled therapy allows functional outcome improvement in patients in RA to greater extent. No therapy control leads to functional outcome worsening in RA. During a long follow-up, there is a reduction in the correlation of the Health Assessment Questionnaire (HAQ) scores with the parameters reflecting disease activity and an increase in the correlation of the HAQ with those reflecting the progression of RA. The development of the structural and anatomic changes in hand periarticular tissues with the formation of irreversible deformities does not correlate with the HAQ score in patients with RA.https://rsp.mediar-press.net/rsp/article/view/1252rheumatoid arthritistreatmentfunctional outcome
spellingShingle Natalya Vladimirovna Chichasova
S A Vladimirov
G R Imametdinova
E V Igolkina
E L Nasonov
Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy
Научно-практическая ревматология
rheumatoid arthritis
treatment
functional outcome
title Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy
title_full Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy
title_fullStr Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy
title_full_unstemmed Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy
title_short Functional outcomes of rheumatoid arthritis during various proceduresof anti-inflammatory therapy
title_sort functional outcomes of rheumatoid arthritis during various proceduresof anti inflammatory therapy
topic rheumatoid arthritis
treatment
functional outcome
url https://rsp.mediar-press.net/rsp/article/view/1252
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AT grimametdinova functionaloutcomesofrheumatoidarthritisduringvariousproceduresofantiinflammatorytherapy
AT evigolkina functionaloutcomesofrheumatoidarthritisduringvariousproceduresofantiinflammatorytherapy
AT elnasonov functionaloutcomesofrheumatoidarthritisduringvariousproceduresofantiinflammatorytherapy