Subcellular localization of hippocampal ryanodine receptor 2 and its role in neuronal excitability and memory

A mouse model containing a GFP-tagged ryanodine receptor 2 (RyR2) has shed light on the precise subcellular localization of hippocampal RyR2 and mechanisms underlying neuronal excitability, learning, and memory.

Bibliographic Details
Main Authors: Florian Hiess, Jinjing Yao, Zhenpeng Song, Bo Sun, Zizhen Zhang, Junting Huang, Lina Chen, Adam Institoris, John Paul Estillore, Ruiwu Wang, Henk E. D. J. ter Keurs, Peter K. Stys, Grant R. Gordon, Gerald W. Zamponi, Anutosh Ganguly, S. R. Wayne Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03124-2