Difficulties of differential diagnosis of portal hypertension: case report

In the article we analysed the difficulties of differential diagnosis of portal hypertension, considers a clinical case that illustrates the presented theoretical material. In the presented clinical observation, the patient’s disease was manifested by bleeding from the varicose veins of the esophagu...

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Main Authors: T. V. Penkina, O. E. Berezutskaya, D. T. Dicheva, E. V. Partsvania-Vinogradova, V. S. Larina, R. M. Umyarova, D. V. Borzova, E. V. Ulyankina
Format: Article
Language:Russian
Published: Remedium Group LLC 2021-05-01
Series:Медицинский совет
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Online Access:https://www.med-sovet.pro/jour/article/view/6172
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author T. V. Penkina
O. E. Berezutskaya
D. T. Dicheva
E. V. Partsvania-Vinogradova
V. S. Larina
R. M. Umyarova
D. V. Borzova
E. V. Ulyankina
author_facet T. V. Penkina
O. E. Berezutskaya
D. T. Dicheva
E. V. Partsvania-Vinogradova
V. S. Larina
R. M. Umyarova
D. V. Borzova
E. V. Ulyankina
author_sort T. V. Penkina
collection DOAJ
description In the article we analysed the difficulties of differential diagnosis of portal hypertension, considers a clinical case that illustrates the presented theoretical material. In the presented clinical observation, the patient’s disease was manifested by bleeding from the varicose veins of the esophagus. In most cases, portal hypertension syndrome in practicing clinicians is associated with liver cirrhosis, however, it is necessary to remember about the possibility of developing subhepatic portal hypertension, in particular as a result of the formation of portal vein thrombosis. If there are signs of portal hypertension, it is necessary to specify the level of obstruction to blood flow, that is, the form of portal hypertension (subhepatic, hepatic, suprahepatic). Often, portal vein thrombosis can be formed due to undiagnosed blood diseases that occur without any clinical symptoms. The provided clinical example demonstrates a case of portal hypertension in the outcome of a chronic form of myeloproliferative syndrome. Portal cavernoma is quite rare and it is formed due to multiple small-diameter venous structures that gradually replace the occluded vessel with a system of collaterals proximal and distal to the portal vein thrombosis site. In the formation of the diagnosis the main are radiation research methods, but the conclusions should be considered only in conjunction with the clinical evidence. The clinical case is interesting because a large cavernoma of the portal vein in a patient with subhepatic portal hypertension was regarded as a «solid formation» according to magnetic resonance tomography. According to the literature data, cavernous transformation has an external similarity to the tumor process, which expands the range of differential diagnosis and requires the exclusion of oncological formations.
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spelling doaj.art-9b9d04b60657481cab2a25b1bd09d93e2023-04-23T06:56:56ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902021-05-01059210110.21518/2079-701X-2021-5-92-1015601Difficulties of differential diagnosis of portal hypertension: case reportT. V. Penkina0O. E. Berezutskaya1D. T. Dicheva2E. V. Partsvania-Vinogradova3V. S. Larina4R. M. Umyarova5D. V. Borzova6E. V. Ulyankina7Main Clinical Hospital of the Ministry of Internal Affairs of the Russian FederationMain Clinical Hospital of the Ministry of Internal Affairs of the Russian FederationYevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of RussiaYevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of RussiaMain Clinical Hospital of the Ministry of Internal Affairs of the Russian FederationYevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of RussiaYevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of RussiaYevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of RussiaIn the article we analysed the difficulties of differential diagnosis of portal hypertension, considers a clinical case that illustrates the presented theoretical material. In the presented clinical observation, the patient’s disease was manifested by bleeding from the varicose veins of the esophagus. In most cases, portal hypertension syndrome in practicing clinicians is associated with liver cirrhosis, however, it is necessary to remember about the possibility of developing subhepatic portal hypertension, in particular as a result of the formation of portal vein thrombosis. If there are signs of portal hypertension, it is necessary to specify the level of obstruction to blood flow, that is, the form of portal hypertension (subhepatic, hepatic, suprahepatic). Often, portal vein thrombosis can be formed due to undiagnosed blood diseases that occur without any clinical symptoms. The provided clinical example demonstrates a case of portal hypertension in the outcome of a chronic form of myeloproliferative syndrome. Portal cavernoma is quite rare and it is formed due to multiple small-diameter venous structures that gradually replace the occluded vessel with a system of collaterals proximal and distal to the portal vein thrombosis site. In the formation of the diagnosis the main are radiation research methods, but the conclusions should be considered only in conjunction with the clinical evidence. The clinical case is interesting because a large cavernoma of the portal vein in a patient with subhepatic portal hypertension was regarded as a «solid formation» according to magnetic resonance tomography. According to the literature data, cavernous transformation has an external similarity to the tumor process, which expands the range of differential diagnosis and requires the exclusion of oncological formations.https://www.med-sovet.pro/jour/article/view/6172portal hypertensionportal vein thrombosiscavernomachronic myeloproliferative diseaseliver cirrhosis
spellingShingle T. V. Penkina
O. E. Berezutskaya
D. T. Dicheva
E. V. Partsvania-Vinogradova
V. S. Larina
R. M. Umyarova
D. V. Borzova
E. V. Ulyankina
Difficulties of differential diagnosis of portal hypertension: case report
Медицинский совет
portal hypertension
portal vein thrombosis
cavernoma
chronic myeloproliferative disease
liver cirrhosis
title Difficulties of differential diagnosis of portal hypertension: case report
title_full Difficulties of differential diagnosis of portal hypertension: case report
title_fullStr Difficulties of differential diagnosis of portal hypertension: case report
title_full_unstemmed Difficulties of differential diagnosis of portal hypertension: case report
title_short Difficulties of differential diagnosis of portal hypertension: case report
title_sort difficulties of differential diagnosis of portal hypertension case report
topic portal hypertension
portal vein thrombosis
cavernoma
chronic myeloproliferative disease
liver cirrhosis
url https://www.med-sovet.pro/jour/article/view/6172
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AT evpartsvaniavinogradova difficultiesofdifferentialdiagnosisofportalhypertensioncasereport
AT vslarina difficultiesofdifferentialdiagnosisofportalhypertensioncasereport
AT rmumyarova difficultiesofdifferentialdiagnosisofportalhypertensioncasereport
AT dvborzova difficultiesofdifferentialdiagnosisofportalhypertensioncasereport
AT evulyankina difficultiesofdifferentialdiagnosisofportalhypertensioncasereport