Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience

Hashimoto’s thyroiditis is the most common cause of hypothyroidism in the iodine-sufficient areas of the world. Differentiated thyroid cancer is the most common thyroid cancer subtype, accounting for more than 95% of cases, and it is considered a tumor with a good prognosis, although a certain numbe...

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Main Authors: Federico Cappellacci, Gian Luigi Canu, Maria Letizia Lai, Eleonora Lori, Miriam Biancu, Francesco Boi, Fabio Medas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.959595/full
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author Federico Cappellacci
Gian Luigi Canu
Maria Letizia Lai
Eleonora Lori
Miriam Biancu
Francesco Boi
Fabio Medas
author_facet Federico Cappellacci
Gian Luigi Canu
Maria Letizia Lai
Eleonora Lori
Miriam Biancu
Francesco Boi
Fabio Medas
author_sort Federico Cappellacci
collection DOAJ
description Hashimoto’s thyroiditis is the most common cause of hypothyroidism in the iodine-sufficient areas of the world. Differentiated thyroid cancer is the most common thyroid cancer subtype, accounting for more than 95% of cases, and it is considered a tumor with a good prognosis, although a certain number of patients experience a poor clinical outcome. Hashimoto’s thyroiditis has been found to coexist with differentiated thyroid cancer in surgical specimens, but the relationship between these two entities has not yet been clarified. Our study aims to analyze the relationship between these two diseases, highlighting the incidence of histological diagnosis of Hashimoto thyroiditis in differentiated thyroid cancer patients, and assess how this autoimmune disorder influences the risk of structural disease recurrence and recurrence rate.
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spelling doaj.art-9ba8071652e74c048210fe85104948532022-12-22T02:14:29ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-07-011210.3389/fonc.2022.959595959595Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experienceFederico Cappellacci0Gian Luigi Canu1Maria Letizia Lai2Eleonora Lori3Miriam Biancu4Francesco Boi5Fabio Medas6Department of Surgical Sciences, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, University of Cagliari, Cagliari, ItalyDepartment of Cytomorphology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Science, Sapienza University of Rome, Rome, ItalyDepartment of Surgical Sciences, University of Cagliari, Cagliari, ItalyEndocrinology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, University of Cagliari, Cagliari, ItalyHashimoto’s thyroiditis is the most common cause of hypothyroidism in the iodine-sufficient areas of the world. Differentiated thyroid cancer is the most common thyroid cancer subtype, accounting for more than 95% of cases, and it is considered a tumor with a good prognosis, although a certain number of patients experience a poor clinical outcome. Hashimoto’s thyroiditis has been found to coexist with differentiated thyroid cancer in surgical specimens, but the relationship between these two entities has not yet been clarified. Our study aims to analyze the relationship between these two diseases, highlighting the incidence of histological diagnosis of Hashimoto thyroiditis in differentiated thyroid cancer patients, and assess how this autoimmune disorder influences the risk of structural disease recurrence and recurrence rate.https://www.frontiersin.org/articles/10.3389/fonc.2022.959595/fullhashimoto thyroiditisdifferentiated thyroid cancerthyroid surgerypapillary thyroid cancerthyroid
spellingShingle Federico Cappellacci
Gian Luigi Canu
Maria Letizia Lai
Eleonora Lori
Miriam Biancu
Francesco Boi
Fabio Medas
Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience
Frontiers in Oncology
hashimoto thyroiditis
differentiated thyroid cancer
thyroid surgery
papillary thyroid cancer
thyroid
title Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience
title_full Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience
title_fullStr Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience
title_full_unstemmed Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience
title_short Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience
title_sort association between hashimoto thyroiditis and differentiated thyroid cancer a single center experience
topic hashimoto thyroiditis
differentiated thyroid cancer
thyroid surgery
papillary thyroid cancer
thyroid
url https://www.frontiersin.org/articles/10.3389/fonc.2022.959595/full
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