The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else,...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Brasileira de Divulgação Científica
2001-02-01
|
| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 |
| _version_ | 1819029863503233024 |
|---|---|
| author | R. Andreatini C. Blanchard R. Blanchard M.L. Brandão A.P. Carobrez G. Griebel F.S. Guimarães S.L. Handley F. Jenck J.R. Leite J. Rodgers L.C. Schenberg C. Da Cunha F.G. Graeff |
| author_facet | R. Andreatini C. Blanchard R. Blanchard M.L. Brandão A.P. Carobrez G. Griebel F.S. Guimarães S.L. Handley F. Jenck J.R. Leite J. Rodgers L.C. Schenberg C. Da Cunha F.G. Graeff |
| author_sort | R. Andreatini |
| collection | DOAJ |
| description | This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification. |
| first_indexed | 2024-12-21T06:21:01Z |
| format | Article |
| id | doaj.art-9bac16a38fae456196ff4397fbd4e055 |
| institution | Directory Open Access Journal |
| issn | 0100-879X 1414-431X |
| language | English |
| last_indexed | 2024-12-21T06:21:01Z |
| publishDate | 2001-02-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-9bac16a38fae456196ff4397fbd4e0552022-12-21T19:13:14ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X1414-431X2001-02-0134214515410.1590/S0100-879X2001000200001The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basisR. AndreatiniC. BlanchardR. BlanchardM.L. BrandãoA.P. CarobrezG. GriebelF.S. GuimarãesS.L. HandleyF. JenckJ.R. LeiteJ. RodgersL.C. SchenbergC. Da CunhaF.G. GraeffThis article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001panicanxietyfearanxiolytics5-HTbenzodiazepinesserotoninamygdalaperiaqueductal gray matteranimal models |
| spellingShingle | R. Andreatini C. Blanchard R. Blanchard M.L. Brandão A.P. Carobrez G. Griebel F.S. Guimarães S.L. Handley F. Jenck J.R. Leite J. Rodgers L.C. Schenberg C. Da Cunha F.G. Graeff The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis Brazilian Journal of Medical and Biological Research panic anxiety fear anxiolytics 5-HT benzodiazepines serotonin amygdala periaqueductal gray matter animal models |
| title | The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
| title_full | The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
| title_fullStr | The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
| title_full_unstemmed | The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
| title_short | The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
| title_sort | brain decade in debate ii panic or anxiety from animal models to a neurobiological basis |
| topic | panic anxiety fear anxiolytics 5-HT benzodiazepines serotonin amygdala periaqueductal gray matter animal models |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 |
| work_keys_str_mv | AT randreatini thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT cblanchard thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT rblanchard thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT mlbrandao thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT apcarobrez thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT ggriebel thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT fsguimaraes thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT slhandley thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT fjenck thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT jrleite thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT jrodgers thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT lcschenberg thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT cdacunha thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT fggraeff thebraindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT randreatini braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT cblanchard braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT rblanchard braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT mlbrandao braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT apcarobrez braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT ggriebel braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT fsguimaraes braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT slhandley braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT fjenck braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT jrleite braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT jrodgers braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT lcschenberg braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT cdacunha braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis AT fggraeff braindecadeindebateiipanicoranxietyfromanimalmodelstoaneurobiologicalbasis |